Evidence map›Paper›PMID 26969406›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2016

Taking forward the World TB Day 2016 theme 'Unite to End Tuberculosis' for the WHO Africa Region.

Francine Ntoumi, Pontiano Kaleebu, Eusebio Macete, Sayoki Mfinanga, Jeremiah Chakaya, Dorothy Yeboah-Manu, Matthew Bates, Peter Mwaba, Markus Maeurer, Eskild Petersen and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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  12. Impact of infectious disease epidemics on tuberculosis diagnostic, management, and prevention services: experiences and lessons from the 2014-2015 Ebola virus disease outbreak in West Africa.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 12 countries.

Francine NtoumiFondation Congolaise pour la Recherche Médicale, Brazzaville, Republic of Congo; Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany. Electronic address: fntoumi@fcrm-congo.com.
Pontiano KaleebuUganda Virus Research Institute Research Unit on AIDS, Entebbe, Uganda.
Eusebio MaceteCentro de Investigação em Saude de Manhiça, and National Directare of Public Health, Ministry of Health, Maputo, Mozambique.
Sayoki MfinangaMuhimbili Medical Research Centre, National Institute for Medical Research, Dar es Salaam, Tanzania.
Jeremiah ChakayaDepartment of Medicine, Dermatology and Psychiatry, Kenyatta University, Nairobi, Kenya.
Dorothy Yeboah-ManuNoguchi Memorial Institute for Medical Research, Accra, Ghana.
Matthew BatesUNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka, Zambia.
Peter MwabaUNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka, Zambia; Ministry of Health, Lusaka, Zambia.
Markus MaeurerDivision of Therapeutic Immunology, Department of Laboratory Medicine, Karolinska Institutet, and Centre for Allogeneic Stem Cell Transplantation, Karolinska University Hospital, Stockholm, Sweden.
Eskild PetersenUniversity of Aarhus, Aarhus, Denmark; The Royal Hospital, Muscat, Oman.
Alimuddin ZumlaUNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka, Zambia; Division of Infection and Immunity, University College London, and NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, UK.
University of Zambia · ZMFondation Congolaise Pour La Recherche Médicale · CGKarolinska Institutet · SEKenyatta University · KEManhiça Health Research Centre · MZNational Institute for Medical Research · TZNoguchi Memorial Institute for Medical Research · GHRoyal Hospital · OMUganda Virus Research Institute · UGUniversity Teaching Hospital · ZM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) remains a global emergency, with an estimated 9.6 million new TB cases worldwide reported in 2014. Twenty-eight percent of these cases were in the World Health Organization (WHO) Africa Region, where the annual case detection rate was 281 per 100000 population-more than double the global average of 133 per 100000. Of the 9.6 million people who developed TB, an estimated 1.2 million (12%) were HIV-positive, and the Africa Region accounted for 74% of these cases. Three million people with TB remain undiagnosed and untreated. Globally, an estimated 480000 had multidrug-resistant TB (MDR-TB). Whilst of the African countries, only South Africa has reported a high prevalence of MDR-TB, it is likely that all of Sub-Saharan Africa has an unreported high load of drug-resistant TB. Tragically, in 2014, only 48% of individuals diagnosed with MDR-TB had successful treatment and an estimated 190000 people died of MDR-TB. Of the global TB funding gap of US$ 0.8 billion, the largest funding gap was in the Africa Region, amounting to US$ 0.4 billion in 2015. The MDR-TB pandemic in particular now threatens to devastate entire regions and may fundamentally alter the life-expectancy and demographic profile of many countries in Sub-Saharan Africa. The theme designated for this year's World TB Day, March 24, 2016, is 'Unite to End TB'. From the Africa Region, there is an urgent need to seriously address the political, economic, and social factors that influence host-Mycobacterium tuberculosis interactions and result in disease. Recent political and funder initiatives that provide renewed hope for the alleviation of Africa's TB and TB/HIV problems are discussed.

Indexed as

Global HealthAfricaAntitubercular AgentsDisease EradicationHIV SeropositivityHumansMycobacterium tuberculosisPrevalenceTuberculosisTuberculosis, Multidrug-ResistantWorld Health OrganizationAntitubercular AgentsAdvocacyEDCTPMultidrug-resistant TBTreatmentTuberculosisUniteWorld TB Day

Identifiers

PMID26969406
PMCPMC7110434
OpenAlexW2293232065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.