Evidence map›Paper›PMID 26969301›Full record

ArticleInternational journal of oral and maxillofacial surgery2016

Association of serum electrolytes and smoking with salivary gland stone formation.

A J Yiu, A Kalejaiye, R L Amdur, H N Todd Hesham, B C Bandyopadhyay

Abstract read
In one paragraph

Article in International journal of oral and maxillofacial surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Multiple Faces of Cervical Lesions in Children.Diagnostics (Basel, Switzerland) · 2022
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

A J YiuCalcium Signaling Laboratory, Research Service, Department of Veterans Affairs Medical Center, Washington, DC, USA.
A KalejaiyeCalcium Signaling Laboratory, Research Service, Department of Veterans Affairs Medical Center, Washington, DC, USA; ENT Head and Neck Section, Surgical Service, Department of Veterans Affairs Medical Center, Washington, DC, USA.
R L AmdurBiostatistics Core, Department of Veterans Affairs Medical Center, Washington, DC, USA.
H N Todd HeshamENT Head and Neck Section, Surgical Service, Department of Veterans Affairs Medical Center, Washington, DC, USA.
B C BandyopadhyayCalcium Signaling Laboratory, Research Service, Department of Veterans Affairs Medical Center, Washington, DC, USA. Electronic address: bidhan.bandyopadhyay@va.gov.
Veterans Health Administration · US

Funding

Calcium transport in kidney proximal tubule and calcium phosphate stone formationR01DK102043 · NIDDK · INSTITUTE FOR CLINICAL RESEARCH, INC. · PI BANDYOPADHYAY, BIDHAN CHANDRA · 2015 to 2019
$1.1M
Function of TRPC3 in salivary glandR03DE019524 · NIDCR · INSTITUTE FOR CLINICAL RESEARCH, INC. · PI BANDYOPADHYAY, BIDHAN CHANDRA · 2010 to 2011
$199k
NIDCR NIH HHS R03 DE019524NIDDK NIH HHS R01 DK102043
6 · The paper itself

Abstract

To further define potential factors that may contribute to stone formation in salivary glands (sialolithiasis), a retrospective chart review was performed of patients diagnosed with sialolithiasis between March 1, 1998 and February 29, 2012. Information on salivary gland stone number, location and size, medical history, medications, and serum electrolyte levels were collected. Associations between electrolyte levels and stone characteristics (such as stone number and size) were examined. Fifty-nine patients were identified; their median age was 58 years (range 25-89 years) and most were male (95%). Salivary stones were most commonly located in the submandibular glands (83%). Thirty-five patients (59%) had a smoking history, with 16 (27%) reported as current smokers. There was a significant association between current smoker status and stone size (mean largest stone size 12.4±8.8mm vs. 7.5±4.8mm in current smokers vs. non-smokers; P=0.03). Serum sodium levels (r=0.32, P=0.014) and serum potassium levels (r=0.31, P=0.017) showed significant positive correlations with stone size. While the aetiology of sialolithiasis remains unclear, smoking (which can contribute to reduced saliva flow) and higher serum sodium levels (which can reflect volume depletion) are associated with larger salivary stones.

Indexed as

AdultAgedAged, 80 and overElectrolytesFemaleHumansMaleMiddle AgedPotassiumRetrospective StudiesSalivary Gland CalculiSmokingSodiumSubmandibular GlandSubmandibular Gland DiseasesElectrolytesPotassiumSodiumdiureticspatient factorserum electrolyte levelssialolithiasissmoking

Identifiers

PMID26969301
PMCPMC4862889
OpenAlexW2293140178

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.