Evidence map›Paper›PMID 26969283›Full record

ArticleMalaria journal2016

Plasmodium falciparum parasitaemia and clinical malaria among school children living in a high transmission setting in western Kenya.

Stella Kepha, Birgit Nikolay, Fred Nuwaha, Charles S Mwandawiro, Joaniter Nankabirwa, Juliet Ndibazza, Jorge Cano, Damaris Matoke-Muhia, Rachel L Pullan, Elizabeth Allen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 51 citations in OpenAlex.

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  2. Exploring theFrontiers in immunology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Stella KephaSchool of Public Health, Makerere University College of Health Sciences, Kampala, Uganda. stellakepha2005@yahoo.com.
Birgit NikolayLondon School of Hygiene and Tropical Medicine, London, UK.
Fred NuwahaSchool of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.
Charles S MwandawiroEastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Joaniter NankabirwaDepartment of Internal Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Juliet NdibazzaDepartment of Internal Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Jorge CanoLondon School of Hygiene and Tropical Medicine, London, UK.
Damaris Matoke-MuhiaCentre of Biotechnology Research and Development, KEMRI, Nairobi, Kenya.
Rachel L PullanLondon School of Hygiene and Tropical Medicine, London, UK.
Elizabeth AllenLondon School of Hygiene and Tropical Medicine, London, UK.
Katherine E HallidayLondon School of Hygiene and Tropical Medicine, London, UK.
Simon J BrookerLondon School of Hygiene and Tropical Medicine, London, UK.
London School of Hygiene & Tropical Medicine · GBMakerere University · UGKenya Medical Research Institute · KE

Funding

Wellcome Trust 087540Wellcome Trust WT084289MA
6 · The paper itself

Abstract

backgroundMalaria among school children is increasingly receiving attention, yet the burden of malaria in this age group is poorly defined. This study presents data on malaria morbidity among school children in Bungoma county, western Kenya.

methodThis study investigated the burden and risk factors of Plasmodium falciparum infection, clinical malaria, and anaemia among 2346 school children aged 5-15 years, who were enrolled in an individually randomized trial evaluating the effect of anthelmintic treatment on the risks of malaria. At baseline, children were assessed for anaemia and nutritional status and information on household characteristics was collected. Children were followed-up for 13 months to assess the incidence of clinical malaria by active detection, and P. falciparum infection and density evaluated using repeated cross-sectional surveys over 15 months.

resultsOn average prevalence of P. falciparum infection was 42% and ranged between 32 and 48% during the five cross-sectional surveys. Plasmodium falciparum prevalence was significantly higher among boys than girls. The overall incidence of clinical malaria was 0.26 episodes per person year (95% confidence interval, 0.24-0.29) and was significantly higher among girls (0.23 versus 0.31, episodes per person years). Both infection prevalence and clinical disease varied by season. In multivariable analysis, P. falciparum infection was associated with being male, lower socioeconomic status and stunting. The risk of clinical malaria was associated with being female.

conclusionThese findings show that the burden of P. falciparum parasitaemia, clinical malaria and anaemia among school children is not insignificant, and suggest that malaria control programmes should be expanded to include this age group.

Indexed as

AdolescentAnemiaChildChild, PreschoolCross-Sectional StudiesFemaleFollow-Up StudiesHumansKenyaMalaria, FalciparumMaleParasitemiaPrevalenceRandomized Controlled Trials as TopicRisk FactorsSchoolsAnaemiaKenyaMalariaSchool children

Identifiers

PMID26969283
PMCPMC4788950
OpenAlexW2293993392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.