Evidence map›Paper›PMID 26968402›Full record

ReviewLipids2016

Sources and Bioactive Properties of Conjugated Dietary Fatty Acids.

Alan A Hennessy, Paul R Ross, Gerald F Fitzgerald, Catherine Stanton

Abstract readReview
PubMed Publisher
In one paragraph

Review in Lipids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. The Antitumor Effects of α-Linolenic Acid.Journal of personalized medicine · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Orlistat-Induced Gut Microbiota Modification in Obese Mice.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Alan A HennessyTeagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, Ireland.
Paul R RossAPC Microbiome Institute, University College Cork, Cork, Ireland.
Gerald F FitzgeraldAPC Microbiome Institute, University College Cork, Cork, Ireland.
Catherine StantonTeagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, Ireland. catherine.stanton@teagasc.ie.
University College Cork · IEAPC Microbiome Institute · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The group of conjugated fatty acids known as conjugated linoleic acid (CLA) isomers have been extensively studied with regard to their bioactive potential in treating some of the most prominent human health malignancies. However, CLA isomers are not the only group of potentially bioactive conjugated fatty acids currently undergoing study. In this regard, isomers of conjugated α-linolenic acid, conjugated nonadecadienoic acid and conjugated eicosapentaenoic acid, to name but a few, have undergone experimental assessment. These studies have indicated many of these conjugated fatty acid isomers commonly possess anti-carcinogenic, anti-adipogenic, anti-inflammatory and immune modulating properties, a number of which will be discussed in this review. The mechanisms through which these bioactivities are mediated have not yet been fully elucidated. However, existing evidence indicates that these fatty acids may play a role in modulating the expression of several oncogenes, cell cycle regulators, and genes associated with energy metabolism. Despite such bioactive potential, interest in these conjugated fatty acids has remained low relative to the CLA isomers. This may be partly attributed to the relatively recent emergence of these fatty acids as bioactives, but also due to a lack of awareness regarding sources from which they can be produced. In this review, we will also highlight the common sources of these conjugated fatty acids, including plants, algae, microbes and chemosynthesis.

Indexed as

Algal ProteinsAnimalsAnticarcinogenic AgentsAnti-Inflammatory AgentsAnti-Obesity AgentsCell Line, TumorDietary FatsDisease Models, AnimalFatsFatty AcidsHumansIsomerismLinoleic Acids, ConjugatedPlant ProteinsAlgal ProteinsAnticarcinogenic AgentsAnti-Inflammatory AgentsAnti-Obesity AgentsDietary FatsFatsFatty AcidsLinoleic Acids, ConjugatedPlant ProteinsConjugated linoleic acid (CLA)Docosahexaenoic acidLipid biochemistryLipid metabolismMetabolism, fatty acidsPolyunsaturated fatty acids (PUFA)

Identifiers

PMID26968402
OpenAlexW2295848014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.