Evidence map›Paper›PMID 26968318›Full record

ArticleMagnetic resonance in medicine2017

Dual-Pathway sequences for MR thermometry: When and where to use them.

Pelin Aksit Ciris, Cheng-Chieh Cheng, Chang-Sheng Mei, Lawrence P Panych, Bruno Madore

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Pelin Aksit CirisDepartment of Biomedical Engineering, Akdeniz University, Antalya, Turkey.
Cheng-Chieh ChengDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Chang-Sheng MeiDepartment of Physics, Soochow University, Taipei, Taiwan.
Lawrence P PanychDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Bruno MadoreDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Harvard University · USBrigham and Women's Hospital · USSoochow University · TW

Funding

Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
Multidisciplinary Training in Image-Guided TherapyR25CA089017 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI FENNESSY, FIONA · 2001 to 2017
$7.8M
Advanced Techniques for Rapid and Artifact-Resistant MR Diffusion ImagingR01EB010195 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI MADORE, BRUNO, MAIER, STEPHAN E · 2010 to 2013
$1.9M
Quantitative and synthetic MR imagingR21EB019500 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI MADORE, BRUNO · 2015 to 2016
$488k
NCI NIH HHS R25 CA089017NIBIB NIH HHS P41 EB015898NIBIB NIH HHS R01 EB010195NIBIB NIH HHS R21 EB019500
6 · The paper itself

Abstract

purposeDual-pathway sequences have been proposed to help improve the temperature-to-noise ratio (TNR) in MR thermometry. The present work establishes how much of an improvement these so-called "PSIF-FISP" sequences may bring in various organs and tissues.

methodsSimulations and TNR calculations were validated against analytical equations, phantom, abdomen, and brain scans. Relative TNRs for PSIF-FISP, as compared to a dual-FISP reference standard, were calculated for flip angle (FA) = 1 to 85 º and repetition time (TR) = 6 to 60 ms, for gray matter, white matter, cervix, endometrium, myometrium, prostate, kidney medulla and cortex, bone marrow, pancreas, spleen, muscle, and liver tissues.

resultsPSIF-FISP was TNR superior in the kidney, pelvis, spleen, or gray matter at most tested TR and FA settings, and benefits increased at shorter TRs. PSIF-FISP was TNR superior in other tissues, e.g., liver, muscle, pancreas, for only short TR settings (20 ms or less). The TNR benefits of PSIF-FISP increased slightly with FA, and strongly with decreasing TR. Up to two- to three-fold reductions in TR with 20% TNR gains were achievable. In any given tissue, TNR performance is expected to further improve with heating, due to changes in relaxation rates.

conclusionDual-pathway PSIF-FISP can improve TNR and acquisition speed over standard gradient-recalled echo sequences, but optimal acquisition parameters are tissue dependent. Magn Reson Med 77:1193-1200, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

Indexed as

AlgorithmsSignal Processing, Computer-AssistedBody TemperatureHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingReproducibility of ResultsSensitivity and SpecificityTemperatureThermographyDESSMR thermometrymultipathway sequencesproton resonance frequency shiftPSIFtemperature-to-noise ratio

Identifiers

PMID26968318
PMCPMC5018245
OpenAlexW2296566285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.