Evidence map›Paper›PMID 26968159›Full record

ArticleBMC palliative care2016

Symptom severity of patients with advanced cancer in palliative care unit: longitudinal assessments of symptoms improvement.

Shu-Yu Tai, Chung-Yin Lee, Chien-Yi Wu, Hui-Ya Hsieh, Joh-Jong Huang, Chia-Tsuan Huang, Chen-Yu Chien

Abstract read
In one paragraph

Article in BMC palliative care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Symptom evolution in the dying.BMJ supportive & palliative care · 2023
    Article
  4. The adult and pediatric palliative care: differences and shared issues.Journal of anesthesia, analgesia and critical care · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Interventions and symptom relief in hospital palliative cancer care: results from a prospective longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  10. Article
  11. Observational
  12. Patient-reported symptoms before palliative radiotherapy predict survival differences.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2018
    Article
  13. Symptoms in Advanced Cancer Patients in a Greek Hospital: a Descriptive StudyAsian Pacific journal of cancer prevention : APJCP · 2018
    Article
  14. Article
  15. Palliative care needs in hospitalized cancer patients: a 5-year follow-up study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shu-Yu TaiGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chung-Yin LeeDepartment of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chien-Yi WuDepartment of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Hui-Ya HsiehDepartment of Nursing, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Joh-Jong HuangDepartment of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chia-Tsuan HuangDepartment of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. chtshu@kmu.edu.tw.
Chen-Yu ChienDepartment of Otorhinolaryngology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. chenyu@cc.kmu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study assessed the symptom severity of patients with advanced cancer in a palliative care unit and explored the factors associated with symptom improvement.

methodsThis study was conducted in a palliative care unit in Taiwan between October 2004 and December 2009. Symptom intensity was measured by the "Symptom Reporting Form", and graded on a scale of 0 to 4 (0 = none, and 4 = extreme). These measures were assessed on the 1(st), 3(rd), 5(th), and 7(th) Day in the palliative care unit. The study data comprised routine clinical records and patients' demographic data. Generalized estimating equation (GEE) was used to assess the symptom improvement, and investigate the factors associated with the symptom reporting form scores.

resultsAmong the 824 recruited patients with advanced cancer, pain (78.4%), anorexia (64.4%) and constipation (63.5%) were the most common and severe symptom. After controlling for other factors in the multivariate GEE model, the day of palliative care administration was a significant factor associated with all of the scales, except Days 7 on the dyspnoea and oedema scales and Day 5 on the anxiety scale. In addition, patients aged ≥ 65 years exhibited significantly lower scores on the pain, sleep disturbance, depression, and anxiety scales than did those aged < 65 years. Moreover, female patients exhibited higher scores on the vomiting, anorexia, oedema, depression, and anxiety scales than did male patients. Furthermore, patients with gastrointestinal tract cancer exhibited higher scores on the constipation, vomiting, anorexia, oedema, depression, and anxiety scales and lower scores on the dyspnoea scale than did those with lung cancer. Patients with breast cancer exhibited higher scores on the oedema scale and lower scores on the anxiety scale. Patients with genitourinary cancer exhibited higher scores on the vomiting and oedema scales and lower scores on the dyspnoea scale. Patients with head, neck, and oral cancer exhibited lower scores on the oedema scale alone.

conclusionThe symptom severity declined during the first week in the palliative care unit. In addition, differences in sex and primary cancer sites may contribute to varying degrees of symptom improvement.

Indexed as

Palliative CareSeverity of Illness IndexAdultAgedAged, 80 and overAnorexiaAnxietyConstipationDepressionDyspneaFemaleHumansLongitudinal StudiesMaleMiddle AgedNeoplasmsAdvanced cancerGeneralised estimating equationPalliative careSymptom severity

Identifiers

PMID26968159
PMCPMC4787050

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.