ArticlePancreas2016
Clinical Profile, Etiology, and Treatment of Chronic Pancreatitis in North American Women: Analysis of a Large Multicenter Cohort.
Article in Pancreas, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Pancrelipase Improves Symptoms of Exocrine Pancreatic Insufficiency and Health-Related Quality of Life in a Real-World Population of Patients with Chronic Pancreatitis.Digestive diseases and sciences · 2026Observational
- Idiopathic chronic pancreatitis: clinical highlights.Therapeutic advances in gastroenterology · 2026Review
- Global, regional and national burden of pancreatitis in children and adolescents, 1990-2021: a systematic analysis for the global burden of disease study 2021.Annals of medicine · 2025Article
- Pancreatic Cystic Lesions in the Older Patient: A Review of Clinical Guidelines and Management.Current gastroenterology reports · 2025Review
- Risk factors for calcification in chronic pancreatitis: a systematic review and meta-analysis.Frontiers in medicine · 2025Article
- Impact of sex and comorbid diabetes on hospitalization outcomes in acute pancreatitis: A large United States population-based study.AIMS public health · 2023Article
- Impact of genetic testing and smoking on the distribution of risk factors in patients with recurrent acute and chronic pancreatitis.Scandinavian journal of gastroenterology · 2022Article
- Considering Sex as a Biological Variable in Basic and Clinical Studies: An Endocrine Society Scientific Statement.Endocrine reviews · 2021Article
- Sex-Related Differences of Acute and Chronic Pancreatitis in Adults.Journal of clinical medicine · 2021Review
- Turkish Gastroenterology Association, Pancreas Study Group, Chronic Pancreatitis Committee Consensus Report.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- Constant-severe pain in chronic pancreatitis is associated with genetic loci for major depression in the NAPS2 cohort.Journal of gastroenterology · 2020Article
- Genetic Variants, Fat Malabsorption, and Ancestral Background in a Small Chronic Pancreatitis Cohort.Pancreas · 2020Article
- Lifetime Drinking History of Persons With Chronic Pancreatitis.Alcohol and alcoholism (Oxford, Oxfordshire) · 2019Article
- Article
- Pancreatitis in Children.Gastroenterology · 2019Review
- Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors.Journal of pediatric gastroenterology and nutrition · 2019Article
- Fecal Fat Analyses in Chronic Pancreatitis Importance of Fat Ingestion before Stool Collection.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 6 institutions in 1 country.
Funding
Abstract
objectiveHistorically, chronic pancreatitis (CP) was considered a disease of alcoholic males, but recent data suggest its etiology to be complex. To better understand CP in women, we compared data on women and men with CP in a large, prospectively ascertained multicenter US cohort.
methodsPatients with CP enrolled in the NAPS2 Continuation and Validation study were studied. Information on demographics, etiology, risk factors, phenotype, and treatment(s) used was obtained from detailed questionnaires completed by the patients and physicians.
resultsOf 521 cases, 45% were women. Women were significantly (P < 0.05) less likely to have alcohol etiology (30% vs 58.5%) and more likely to have nonalcoholic etiologies (idiopathic, 32% vs 18%; obstructive, 12% vs 2.4%; genetic, 12.8% vs 7.3%). Demographics, pain experience, morphologic findings, exocrine and endocrine insufficiency, CP-related disability, and use of medical therapies were mostly similar in both sexes. Sphincterotomy (biliary, 33% vs 24%; pancreatic, 38% vs 28%; P < 0.05) was performed more frequently in women, whereas cyst/pseudocyst operations were more common in men (6.6 vs 2.6%, P = 0.02).
conclusionsMost CP cases in women are from nonalcoholic etiologies. In contrast to many other chronic diseases, clinical phenotype of CP is determined by the disease and is independent of sex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.