Evidence map›Paper›PMID 26967292›Full record

ReviewCell2016

Insights into the Neural and Genetic Basis of Vocal Communication.

Genevieve Konopka, Todd F Roberts

Abstract readReview
In one paragraph

Review in Cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

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  19. Evolution of regulatory signatures in primate cortical neurons at cell-type resolution.Proceedings of the National Academy of Sciences of the United States of America · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Genevieve KonopkaDepartment of Neuroscience, UT Southwestern Medical Center, Dallas, TX 75390-9111, USA. Electronic address: genevieve.konopka@utsouthwestern.edu.
Todd F RobertsDepartment of Neuroscience, UT Southwestern Medical Center, Dallas, TX 75390-9111, USA. Electronic address: todd.roberts@utsouthwestern.edu.

Funding

Human Specific Brain DNA Methylation and Neuropsychiatric DiseasesR01MH103517 · NIMH · GEORGIA INSTITUTE OF TECHNOLOGY · PI JORDAN, IRVING KING, PREUSS, TODD M · 2015 to 2019
$3.5M
The role of Foxp1-regulated signaling pathways in brain development and behaviorR01MH102603 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI KONOPKA, GENEVIEVE · 2015 to 2019
$2.2M
Functional dissection of mammalian vocal communicationR01DC014702 · NIDCD · UT SOUTHWESTERN MEDICAL CENTER · PI KONOPKA, GENEVIEVE · 2016 to 2020
$1.7M
Neuronal circuit mechanisms for learning during social interactionsR01DC014364 · NIDCD · UT SOUTHWESTERN MEDICAL CENTER · PI ROBERTS, TODD F · 2015 to 2019
$1.4M
Identification of human-relevant CLOCK molecular signaling pathwaysR21MH107672 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI KONOPKA, GENEVIEVE · 2015 to 2016
$445k
NIDCD NIH HHS R01 DC014364NIDCD NIH HHS R01DC014364NIDCD NIH HHS R01 DC014702NIDCD NIH HHS R01DC014702NIMH NIH HHS R01 MH102603NIMH NIH HHS R01MH102603NIMH NIH HHS R01 MH103517NIMH NIH HHS R01MH103517NIMH NIH HHS R21 MH107672NIMH NIH HHS R21MH107672
6 · The paper itself

Abstract

The use of vocalizations to communicate information and elaborate social bonds is an adaptation seen in many vertebrate species. Human speech is an extreme version of this pervasive form of communication. Unlike the vocalizations exhibited by the majority of land vertebrates, speech is a learned behavior requiring early sensory exposure and auditory feedback for its development and maintenance. Studies in humans and a small number of other species have provided insights into the neural and genetic basis for learned vocal communication and are helping to delineate the roles of brain circuits across the cortex, basal ganglia, and cerebellum in generating vocal behaviors. This Review provides an outline of the current knowledge about these circuits and the genes implicated in vocal communication, as well as a perspective on future research directions in this field.

Indexed as

SpeechVocalization, AnimalAnimalsBrainForkhead Transcription FactorsHumansLearningNervous System DiseasesNeural PathwaysForkhead Transcription FactorsFOXP2human brainlanguagesensorimotor circuitssongbirdspeech

Identifiers

PMID26967292
PMCPMC4788808

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.