Evidence map›Paper›PMID 26967287›Full record

ReviewCell2016

Hardwiring Stem Cell Communication through Tissue Structure.

Tianchi Xin, Valentina Greco, Peggy Myung

Abstract readReview
In one paragraph

Review in Cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Successful oocyte transport through the oviduct does not depend on the longitudinal alignment of oviduct epithelial folds.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Starve-Feed Cycles Direct Quiescence to Proliferation Transitions inbioRxiv : the preprint server for biology · 2026
    Article
  6. Regenerative potential of CD200Frontiers in cell and developmental biology · 2026
    Article
  7. bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. The development of hair follicles and nail.Developmental biology · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Tracing the developmental origin of tissue stem cells.Development, growth & differentiation · 2022
    Review
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tianchi XinDepartment of Genetics, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Valentina GrecoDepartment of Genetics, Yale School of Medicine, New Haven, Connecticut 06510, USA; Department of Dermatology, Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut 06510, USA; Department of Cell Biology, Yale Stem Cell Center, Yale School of Medicine, New Haven, Connecticut 06510, USA; Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut 06510, USA. Electronic address: valentina.greco@yale.edu.
Peggy MyungDepartment of Dermatology, Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut 06510, USA; Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut 06510, USA. Electronic address: peggy.myung@yale.edu.

Funding

Live Imaging of Skin RegenerationR01AR063663 · NIAMS · YALE UNIVERSITY · PI Valentina Greco · 2012 to 2026
$7.7M
Normal stem cells and their transition to disease in the skinR01AR067755 · NIAMS · YALE UNIVERSITY · PI GRECO, VALENTINA · 2016 to 2020
$2.2M
The Role of Non-Cell Autonomous Wnt Activation in Hair Follicle Growth and CancerK08AR066790 · NIAMS · YALE UNIVERSITY · PI MYUNG, PEGGY S · 2014 to 2018
$674k
Dissecting the Temporal Role of Dermal Wnt/Beta-Catenin Signaling in Hair Follicle Induction During Development and Regenerative Wound HealingR03AR072807 · NIAMS · YALE UNIVERSITY · PI MYUNG, PEGGY S · 2018 to 2019
$168k
NIAMS NIH HHS 1K08AR066790-01NIAMS NIH HHS 1R01AR063663-01NIAMS NIH HHS K08 AR066790NIAMS NIH HHS R01 AR063663NIAMS NIH HHS R01 AR067755NIAMS NIH HHS R03 AR072807
6 · The paper itself

Abstract

Adult stem cells across diverse organs self-renew and differentiate to maintain tissue homeostasis. How stem cells receive input to preserve tissue structure and function largely relies on their communication with surrounding cellular and non-cellular elements. As such, how tissues are organized and patterned not only reflects organ function, but also inherently hardwires networks of communication between stem cells and their environment to direct tissue homeostasis and injury repair. This review highlights how different methods of stem cell communication reflect the unique organization and function of diverse tissues.

Indexed as

Cell CommunicationAdult Stem CellsAnimalsHomeostasisHumansRegenerationStem Cells

Identifiers

PMID26967287
PMCPMC4805424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.