Observational studyJournal of Alzheimer's disease : JAD2016
Nutritional Status is Associated with Faster Cognitive Decline and Worse Functional Impairment in the Progression of Dementia: The Cache County Dementia Progression Study1.
Observational study in Journal of Alzheimer's disease : JAD, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed, 93 citations in OpenAlex.
- Association of serum uric acid levels with cognitive function in the hypertensive population: a cross-sectional study.BMC neurology · 2026Article
- Associations between pulmonary function and depression: evidence from the CHARLS cohort 2015-2018.Frontiers in public health · 2025Article
- Frailty, malnutrition, healthcare utilization, and mortality in patients with dementia and cognitive impairment obtained from hospital administrative data.Frontiers in medicine · 2025Article
- The Association of Cognitive Impairment and Depression with Malnutrition among Vulnerable, Community-Dwelling Older Adults: A Large Cross-Sectional Study.Geriatrics (Basel, Switzerland) · 2024Article
- Explainable AI and transformer models: Unraveling the nutritional influences on Alzheimer's disease mortality.Smart health (Amsterdam, Netherlands) · 2024Article
- Prevention, Assessment, and Management of Malnutrition in Older Adults with Early Stages of Cognitive Disorders.Nutrients · 2024Review
- Understanding the impact related to lifestyle interventions for people with dementia: A systematic review protocol.PloS one · 2024Article
- Malnutrition and neuropsychiatric symptoms in dementia: the Cache County Dementia Progression Study.International psychogeriatrics · 2023Observational
- Dietary pattern, food, and nutritional supplement effects on cognitive outcomes in mild cognitive impairment: a systematic review of previous reviews.Nutrition reviews · 2023Article
- Reduced body cell mass and functions in lower extremities are associated with mild cognitive impairment and Alzheimer's dementia.Scientific reports · 2023Article
- An Exploratory Study of Nutrition Knowledge and Challenges Faced by Informal Carers of Community-Dwelling People with Dementia: Online Survey and Thematic Analysis.Geriatrics (Basel, Switzerland) · 2023Article
- Metabolomics in aging research: aging markers from organs.Frontiers in cell and developmental biology · 2023Review
- Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study.Molecular psychiatry · 2022Article
- Malnutrition is positively associated with cognitive decline in centenarians and oldest-old adults: A cross-sectional study.EClinicalMedicine · 2022Article
- Sarcopenic Obesity Tendency and Nutritional Status Is Related to the Risk of Sarcopenia, Frailty, Depression and Quality of Life in Patients with Dementia.International journal of environmental research and public health · 2022Article
- Moderate increase of serum uric acid within a normal range is associated with improved cognitive function in a non-normotensive population: A nationally representative cohort study.Frontiers in aging neuroscience · 2022Article
- The effect of dietary patterns on mild cognitive impairment and dementia incidence among community-dwelling older adults.Frontiers in nutrition · 2022Article
- Malnutrition Is Associated With Impaired Functional Status in Older People Receiving Home Care Nursing Service.Frontiers in nutrition · 2021Article
- The Influence of Serum Uric Acid Level on Alzheimer's Disease: A Narrative Review.BioMed research international · 2021Review
- The Relationship of Malnutrition With Cognitive Function in the Older Chinese Population: Evidence From the Chinese Longitudinal Healthy Longevity Survey Study.Frontiers in aging neuroscience · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Nutritional status may be a modifiable factor in the progression of dementia. We examined the association of nutritional status and rate of cognitive and functional decline in a U.S. population-based sample. Study design was an observational longitudinal study with annual follow-ups up to 6 years of 292 persons with dementia (72% Alzheimer's disease, 56% female) in Cache County, UT using the Mini-Mental State Exam (MMSE), Clinical Dementia Rating Sum of Boxes (CDR-sb), and modified Mini Nutritional Assessment (mMNA). mMNA scores declined by approximately 0.50 points/year, suggesting increasing risk for malnutrition. Lower mMNA score predicted faster rate of decline on the MMSE at earlier follow-up times, but slower decline at later follow-up times, whereas higher mMNA scores had the opposite pattern (mMNA by time β= 0.22, p = 0.017; mMNA by time2 β= -0.04, p = 0.04). Lower mMNA score was associated with greater impairment on the CDR-sb over the course of dementia (β= 0.35, p < 0.001). Assessment of malnutrition may be useful in predicting rates of progression in dementia and may provide a target for clinical intervention.
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