Evidence map›Paper›PMID 26967018›Full record

ArticleRNA biology2016

A game of tag: MAPS catches up on RNA interactomes.

Marie-Claude Carrier, David Lalaouna, Eric Massé

Abstract read
In one paragraph

Article in RNA biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Small RNAs ofThe Yale journal of biology and medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marie-Claude Carriera Department of Biochemistry , RNA Group, Université de Sherbrooke , Sherbrooke, Québec , Canada.
David Lalaounaa Department of Biochemistry , RNA Group, Université de Sherbrooke , Sherbrooke, Québec , Canada.
Eric Masséa Department of Biochemistry , RNA Group, Université de Sherbrooke , Sherbrooke, Québec , Canada.

Funding

CIHR
6 · The paper itself

Abstract

In the last few decades, small regulatory RNA (sRNA) molecules emerged as key regulators in every kingdom of life. Resolving the full targetome of sRNAs has however remained a challenge. To address this, we used an in vivo tagging MS2-affinity purification protocol coupled with RNA sequencing technology, namely MAPS, to assemble full bacterial small RNAs targetomes. The impressive potential of MAPS has been supported by a number of reports. Here, we concisely overview RNA-tagging history that preceded the development of the MAPS assay and expose the range of possible uses of this technology.

Indexed as

Aptamers, NucleotideBacteriaBacterial ProteinsGene Expression Regulation, BacterialIndicators and ReagentsProtein BindingRNA-Binding ProteinsRNA, MessengerRNA, Small UntranslatedSequence Analysis, RNAStreptavidinStreptomycinAptamers, NucleotideBacterial ProteinsIndicators and ReagentsRNA-Binding ProteinsRNA, MessengerRNA, Small UntranslatedStreptavidinStreptomycinAffinity purificationantisenseMS2RNA purificationRNA spongeRNA tagRybBRyhBsRNAtRNA

Identifiers

PMID26967018
PMCPMC4962807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.