ReviewPathology research international2016
Salivary and Urinary Total Antioxidant Capacity as Biomarkers of Oxidative Stress in Humans.
Review in Pathology research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Circulating biomarkers of oxidative stress in people with acne vulgaris: a systematic review and meta-analysis.Archives of dermatological research · 2024Pooled it
- Systematic Review and Meta-Analysis of Oxidative Stress and Antioxidant Markers in Oral Lichen Planus.Oxidative medicine and cellular longevity · 2021Pooled it
- Effects of stannous fluoride dentifrice on gingival health and oxidative stress markers: a prospective clinical trial.BMC oral health · 2024Trial
- Trial
- Impact of asthma on mouth breathing, occlusion and salivary parameters in a group of school-aged children: a cross-sectional study.BMC oral health · 2026Article
- Plasma, Urinary, and Salivary Total Redox Status in Critically Ill Patients with Brain Injury and Secondary Organ Failure.Antioxidants (Basel, Switzerland) · 2026Article
- Salivary Total Antioxidant Capacity of Sportive Adolescents-The Effect of Antioxidant Vitamin Intake with Usual Diet and Physical Exercises.Nutrients · 2025Article
- Assessment of blood and urine total antioxidant and oxidative status in alcohol and acetone fatal poisonings.Scientific reports · 2025Article
- The Rainbow and the Umbrella of Temporomandibular Disorders-Total Antioxidant Capacity and Total Oxidant Status in Patients with Myofascial Pain with Referral.Journal of clinical medicine · 2025Article
- Oxidative Stress in Children and Adolescents: Insights Into Human Biology.American journal of human biology : the official journal of the Human Biology Council · 2025Review
- Total Antioxidant Status in Critically Ill Patients with Traumatic Brain Injury and Secondary Organ Failure-A Systematic Review.Diagnostics (Basel, Switzerland) · 2024Review
- Altered oxidative stress and antioxidant biomarkers concentrations in pregnant individuals exposed to oil and gas sites in Northeastern British Columbia.Toxicological sciences : an official journal of the Society of Toxicology · 2024Article
- Concentrations of Glypican-4, Irisin and Total Antioxidant Status in Women with Metabolic Syndrome: Influence of Physical Activity.Biomolecules · 2024Article
- Platelet-rich plasma attenuates the UPEC-induced cystitis via inhibiting MMP-2,9 activities and downregulation of NGF and VEGF in Canis Lupus Familiaris model.Scientific reports · 2024Article
- Correlation between Oxidative Stress Markers and Periodontal Disease in Dogs.Veterinary sciences · 2024Article
- Effect of In Ovo Administration of a Multi-Strain Probiotic and Zinc Glycine Chelate on Antioxidant Capacity and Selected Immune Parameters in Newly Hatched Chicks.Antioxidants (Basel, Switzerland) · 2023Article
- Maternal oxidative stress during pregnancy associated with emotional and behavioural problems in early childhood: implications for foetal programming.Molecular psychiatry · 2023Article
- Salivary stimulatory effect of novel low level transcutaneous electro neurostimulator in geriatric patients with xerostomia.BMC oral health · 2023Article
- A Pilot Study on Oxidative Stress during the Recovery Phase in Critical COVID-19 Patients in a Rehabilitation Facility: Potential Utility of the PAOTBiomedicines · 2023Article
- Inflammageing and Cardiovascular System: Focus on Cardiokines and Cardiac-Specific Biomarkers.International journal of molecular sciences · 2023Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Total Antioxidant Capacity (TAC) is a biomarker often used in order to investigate oxidative stress in many pathological conditions. Saliva and urine can be collected noninvasively and represent attractive diagnostic fluids for detecting biomarkers of various pathological conditions. The reviewed case-control and intervention studies that measured salivary or urinary TAC revealed that diseases, antioxidant foods, or supplements and age, gender, and lifestyle factors influenced salivary or urinary TAC. Salivary and urinary TAC were particularly affected by oral or renal status, respectively, as well as by infection; therefore these factors must be taken into account in both case-control and intervention studies. Furthermore, some considerations on sample collection and normalization strategies could be made. In particular, unstimulated saliva could be the better approach to measure salivary TAC, whereas 24 h or spontaneous urine collection should be chosen on the basis of the study outcome and of the creatinine clearance. Finally, the uric acid-independent TAC could be the better approach to evaluate red-ox status of body, in particular after nutritional interventions and in diseases associated with hyperuricaemia.
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Registered trials
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