Evidence map›Paper›PMID 26966587›Full record

ArticleArab journal of urology2016

Silodosin vs tamsulosin in the management of distal ureteric stones: A prospective randomised study.

Hazem Elgalaly, Ahmed Sakr, Amr Fawzi, Emad A Salem, Esam Desoky, Ashraf Shahin, Mostafa Kamel

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arab journal of urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 5 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 5 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  4. Alpha-blockers as medical expulsive therapy for ureteral stones.The Cochrane database of systematic reviews · 2018
    Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hazem ElgalalyDepartment of Urology, Zagazig University, Zagazig, Egypt.
Ahmed SakrDepartment of Urology, Zagazig University, Zagazig, Egypt.
Amr FawziDepartment of Urology, Zagazig University, Zagazig, Egypt.
Emad A SalemDepartment of Urology, Zagazig University, Zagazig, Egypt.
Esam DesokyDepartment of Urology, Zagazig University, Zagazig, Egypt.
Ashraf ShahinDepartment of Urology, Zagazig University, Zagazig, Egypt.
Mostafa KamelDepartment of Urology, Zagazig University, Zagazig, Egypt.
Zagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the efficacy of silodosin (8 mg) vs tamsulosin (0.4 mg), as a medical expulsive therapy, in the management of distal ureteric stones (DUS) in terms of stone clearance rate and stone expulsion time. PATIENTS AND

methodsA prospective randomised study was conducted on 115 patients, aged 21-55 years, who had unilateral DUS of ⩽10 mm. Patients were divided into two groups. Group 1 received silodosin (8 mg) and Group 2 received tamsulosin (0.4 mg) daily for 1 month. The patients were followed-up by ultrasonography, plain abdominal radiograph of the kidneys, ureters and bladder, and computed tomography (in some cases).

resultsThere was a significantly higher stone clearance rate of 83% in Group 1 vs 57% in Group 2 (P = 0.007). Group 1 also showed a significant advantage for stone expulsion time and analgesic use. Four patients, two in each group, discontinued the treatment in first few days due to side-effects (orthostatic hypotension). No severe complications were recorded during the treatment period. Retrograde ejaculation was recorded in nine and three patients in Groups 1 and 2, respectively.

conclusionOur data show that silodosin is more effective than tamsulosin in the management of DUS for stone clearance rates and stone expulsion times. A multicentre study on larger scale is needed to confirm the efficacy and safety of silodosin.

Indexed as

DistalDUS, distal ureteric stonesKUB, plain abdominal radiograph of the kidneys, ureters and bladderMET, medical expulsive therapySilodosinStoneSWL, shockwave lithotripsyTamsulosinUreteric

Identifiers

PMID26966587
PMCPMC4767790
OpenAlexW2232023388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.