Evidence map›Paper›PMID 26966553›Full record

ArticleJournal of virus eradication

Women in HIV cure research: multilevel interventions to improve sex equity in recruitment.

Mary E Grewe, Yuntong Ma, Adam Gilbertson, Stuart Rennie, Joseph D Tucker

Abstract read
In one paragraph

Article in Journal of virus eradication. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. The HIV Reservoir and Immune Landscape Across the Life Course of Women: Implications for Cure Strategies.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  3. Article
  4. Article
  5. Mental health, substance use, and risky sexual behaviors among women living with HIV.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Results from a Pre-exposure Prophylaxis Demonstration Project for At-risk Cisgender Women in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Observational
  10. Review
  11. The Prevalence and Burden of Non-AIDS Comorbidities Among Women Living With or at Risk for Human Immunodeficiency Virus Infection in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  12. Screening and Enrollment by Sex in Human Immunodeficiency Virus Clinical Trials in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Sex Differences in HIV Infection.Current HIV/AIDS reports · 2018
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mary E GreweInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Yuntong MaWashington University School of Medicine, St. Louis, MO, USA.
Adam GilbertsonInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; School of Anthropology and Museum Ethnography, University of Oxford, UK.
Stuart RennieUNC Center for Bioethics, Department of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Joseph D TuckerInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; University of North Carolina Project-China, Guangzhou, Guangdong Province, China.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Unintended and Intended Implications of HIV Cure: A Social and Ethical AnalysisR01AI108366 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RENNIE, STUART, TUCKER, JOSEPH DAVID · 2013 to 2017
$2.9M
NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI108366
6 · The paper itself

Abstract

Women are underrepresented in HIV cure research. In this paper we discuss the rationale for including women and propose multilevel strategies to improve sex equity in HIV cure research. The inadequate inclusion of women in HIV cure research is concerning for both scientific and ethical reasons. Biological responses to HIV and HIV treatment, as well as social contexts, differ between men and women, and this may affect the efficacy of curative interventions. Strategies for improving sex equity in HIV cure research include addressing eligibility criteria, adapting recruitment strategies, engaging community members early in the research process, and promoting funder policy changes. We conclude by describing the Gender, Race, and Clinical Experience (GRACE) study, which is one example of how women can be effectively recruited into HIV-related clinical trials. While HIV cure research is currently in the early stages, as it continues to develop it is important to mobilise for adequate inclusion of women.

Indexed as

equityHIV cure researchwomen

Identifiers

PMID26966553
PMCPMC4780361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.