ArticleOxidative medicine and cellular longevity2016
Protective Effect of Parsley Juice (Petroselinum crispum, Apiaceae) against Cadmium Deleterious Changes in the Developed Albino Mice Newborns (Mus musculus) Brain.
Article in Oxidative medicine and cellular longevity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 27 citations in OpenAlex.
- The effects of developmental cadmium exposure on health and disease.Disease models & mechanisms · 2025Review
- The Protective Impact ofNutrients · 2024Article
- Renal health benefits and therapeutic effects of parsley (Frontiers in medicine · 2024Review
- Impact of salicylic acid on the growth and physiological activities of parsley plants under lead toxicity.Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Drinking desalinated seawater for a long time induces anomalies in the development of new-born albino rats.Saudi journal of biological sciences · 2017Article
- Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
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Abstract
Parsley was used as a probe of the current experiment to prevent the behavioral, morphological and biochemical changes in the newborn brain following the administration of cadmium (Cd) to the pregnant mice. The nonanesthetized pregnant mice were given daily parsley juice (Petroselinum crispum) at doses of 20 mg/kg and 10 mg/kg. Pregnant mothers were given Cd at a dose of 30 mg/kg divided into 3 equal times. The newborns have been divided into 6 groups: Group A, mothers did not take treatment; Groups B and C, mothers were treated with low and high dose of parsley, respectively; Group D, mothers were treated only with Cd (perinatal intoxication); Groups E and F, mothers were treated with Cd doses and protected by low and high doses of parsley, respectively. Light microscopy showed that Cd-induced neuronal degeneration by chromatolysis and pyknosis in the brain regions. The low dose of parsley 10 g/kg/day exhibited significant effects in neutralizing and reducing the deleterious changes due to Cd exposure during pregnancy on the behavioral activities, neurotransmitters, oxidative stress, and brain neurons morphology of the mice newborns.
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