Evidence map›Paper›PMID 26966149›Full record

ArticleEuropean heart journal2016

Physical activity, resting heart rate, and atrial fibrillation: the Tromsø Study.

Bente Morseth, Sidsel Graff-Iversen, Bjarne K Jacobsen, Lone Jørgensen, Audhild Nyrnes, Dag S Thelle, Peter Vestergaard, Maja-Lisa Løchen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 8 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 8 syntheses or guidelines pooled it, 195 citations in OpenAlex.

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  15. Resting Heart Rate and Ischemic Stroke in Patients with Heart Failure.Cerebrovascular diseases (Basel, Switzerland) · 2017
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  17. Minimized atrial pacing and atrial fibrillation burden in the DANPACE II trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Bente MorsethDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway School of Sport Sciences, UiT The Arctic University of Norway, 9037 Tromsø, Norway Centre for Clinical Research and Education, University Hospital of North Norway Trust, Tromsø, Norway bente.morseth@uit.no.
Sidsel Graff-IversenDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.
Bjarne K JacobsenDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
Lone JørgensenDepartment of Health and Care Sciences, University of Tromsø, Tromsø, Norway Department of Clinical Therapeutic Services, University Hospital of Northern Norway, Tromsø, Norway.
Audhild NyrnesDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
Dag S ThelleDivision of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway Department of Community Medicine and Public Health, Institute of Medicine, Gothenburg University, Gothenburg, Sweden.
Peter VestergaardDepartment of Clinical Medicine, Aalborg University Hospital, Aalborg, Denmark Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark.
Maja-Lisa LøchenDepartment of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway Department of Cardiology, University Hospital of North Norway, Tromsø, Norway.
UiT The Arctic University of Norway · NOAalborg University Hospital · DKUniversity Hospital of North Norway · NOUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe objective was to examine the association of physical activity and resting heart rate (RHR) with hospital-diagnosed atrial fibrillation (AF) in a Norwegian cohort. METHODS AND

resultsThis prospective study included 20 484 adults (50.3% men) who participated in the third Tromsø Study survey in 1986-87. At baseline, physical activity was assessed by a validated questionnaire, and RHR was objectively measured. Participants were followed from baseline through 2010 with respect to incident cases of hospital-diagnosed AF documented on an electrocardiogram. During a mean follow-up period of 20 years (409 045 person-years), 750 participants (70.5% men) were diagnosed with AF. Compared with the low physical activity group, moderately active individuals had a 19% lower risk of any AF [adjusted hazard ratio (HR) 0.81, 95% confidence interval (CI) 0.68-0.97], whereas highly active had similar risk of AF. Vigorously active individuals showed a non-significantly higher risk of AF (adjusted HR 1.37, 95% CI 0.77-2.43). Risk of AF increased with decreasing RHR (adjusted HR 0.92, 95% CI 0.86-0.98 for each 10 b.p.m. increase in RHR), and RHR < 50 b.p.m. was a risk factor for AF (P < 0.05).

conclusionIn this prospective cohort study, leisure time physical activity was associated with AF in a J-shaped pattern. Moderate physical activity was associated with a reduced risk of AF, whereas higher activity levels attenuated the benefits of moderate activity. Low RHR was a risk factor for AF. Our results support the hypothesis that moderate and vigorous physical activity may affect AF risk via different pathophysiological mechanisms.

Indexed as

ExerciseAtrial FibrillationFemaleHeart RateHumansIncidenceMaleNorwayProspective StudiesRisk FactorsArrhythmiaAtrial fibrillationExercisePhysical activityResting heart rate

Identifiers

PMID26966149
PMCPMC4986028
OpenAlexW2298207690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.