Evidence map›Paper›PMID 26966054›Full record

ArticleBMJ open2016

Prevalence of alcohol and drug use in injured British Columbia drivers.

Jeffrey R Brubacher, Herbert Chan, Walter Martz, William Schreiber, Mark Asbridge, Jeffrey Eppler, Adam Lund, Scott Macdonald, Olaf Drummer, Roy Purssell and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Jeffrey R BrubacherDepartment of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Herbert ChanDepartment of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Walter MartzProvincial Toxicology Centre, Vancouver, British Columbia, Canada.
William SchreiberProvincial Toxicology Centre, Vancouver, British Columbia, Canada Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.
Mark AsbridgeDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Jeffrey EpplerDepartment of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Adam LundDepartment of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Scott MacdonaldUniversity of Victoria, Centre for Addiction Research of British Columbia, Vancouver, British Columbia, Canada.
Olaf DrummerDepartment of Forensic Medicine, Monash University, Melbourne, Victoria, Australia.
Roy PurssellDepartment of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada Provincial Health Services Authority, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
Gary AndolfattoDepartment of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Robert MannProvincial Health Services Authority, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
Rollin BrantFaculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
University of British Columbia · CADalhousie University · CAMonash University · AUProvincial Health Services Authority · CAUniversity of Toronto · CAUniversity of Victoria · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

objectivesDetermine the prevalence of drug use in injured drivers and identify associated demographic factors and crash characteristics.

designProspective cross-sectional study.

settingSeven trauma centres in British Columbia, Canada (2010-2012).

participantsAutomobile drivers who had blood obtained within 6 h of a crash.

main outcome measuresWe analysed blood for cannabis, alcohol and other impairing drugs using liquid chromatography/mass spectrometry (LCMS).

results1097 drivers met inclusion criteria. 60% were aged 20-50 years, 63.2% were male and 29.0% were admitted to hospital. We found alcohol in 17.8% (15.6% to 20.1%) of drivers. Cannabis was the second most common recreational drug: cannabis metabolites were present in 12.6% (10.7% to 14.7%) of drivers and we detected Δ-9-tetrahydrocannabinol (Δ-9-THC) in 7.3% (5.9% to 9.0%), indicating recent use. Males and drivers aged under 30 years were most likely to use cannabis. We detected cocaine in 2.8% (2.0% to 4.0%) of drivers and amphetamines in 1.2% (0.7% to 2.0%). We also found medications including benzodiazepines (4.0% (2.9% to 5.3%)), antidepressants (6.5% (5.2% to 8.1%)) and diphenhydramine (4.7% (3.5% to 6.2%)). Drivers aged over 50 years and those requiring hospital admission were most likely to have used medications. Overall, 40.1% (37.2% to 43.0%) of drivers tested positive for alcohol or at least one impairing drug and 12.7% (10.7% to 14.7%) tested positive for more than one substance.

conclusionsAlcohol, cannabis and a broad range of other impairing drugs are commonly detected in injured drivers. Alcohol is well known to cause crashes, but further research is needed to determine the impact of other drug use, including drug-alcohol and drug-drug combinations, on crash risk. In particular, more work is needed to understand the role of medications in causing crashes to guide driver education programmes and improve public safety.

Indexed as

Accidents, TrafficAdultAlcohol DrinkingAntidepressive AgentsBenzodiazepinesBritish ColumbiaCross-Sectional StudiesDiphenhydramineDrug CombinationsEthanolFemaleHumansIllicit DrugsMaleMarijuana SmokingMiddle AgedAntidepressive AgentsBenzodiazepinesDiphenhydramineDrug CombinationsEthanolIllicit DrugsACCIDENT & EMERGENCY MEDICINEaccidents, trafficEPIDEMIOLOGYPUBLIC HEALTHTOXICOLOGY

Identifiers

PMID26966054
PMCPMC4800149
OpenAlexW2293958011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.