Evidence map›Paper›PMID 26965906›Full record

SynthesisCerebral cortex (New York, N.Y. : 1991)2017

The Right Dorsal Premotor Mosaic: Organization, Functions, and Connectivity.

Sarah Genon, Hai Li, Lingzhong Fan, Veronika I Müller, Edna C Cieslik, Felix Hoffstaedter, Andrew T Reid, Robert Langner, Christian Grefkes, Peter T Fox and 5 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Cerebral cortex (New York, N.Y. : 1991), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  20. Hippocampal metabolic subregions and networks: Behavioral, molecular, and pathological aging profiles.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sarah GenonInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Hai LiBrainnetome Center, Institute of Automation and.
Lingzhong FanBrainnetome Center, Institute of Automation and.
Veronika I MüllerInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Edna C CieslikInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Felix HoffstaedterInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Andrew T ReidInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Robert LangnerInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Christian GrefkesInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Peter T FoxResearch Imaging Institute, University of Texas Health Science Center at San Antonio, TX, USA.
Susanne MoebusCentre for Urban Epidemiology (CUE), Universitätsklinikum Essen, University of Duisburg-Essen, Essen, Germany.
Svenja CaspersInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Katrin AmuntsInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
Tianzi JiangBrainnetome Center, Institute of Automation and.
Simon B EickhoffInstitute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The right dorsal premotor cortex (PMd) of humans has been reported to be involved in a broad range of motor and cognitive functions. We explored the basis of this behavioral heterogeneity by performing a connectivity-based parcellation using meta-analytic approach applied to PMd coactivations. We compared our connectivity-based parcellation results with parcellations obtained through resting-state functional connectivity and probabilistic diffusion tractography. Functional connectivity profiles and behavioral decoding of the resulting PMd subregions allowed characterizing their respective behavior profile. These procedures divided the right PMd into 5 distinct subregions that formed a cognitive-motor gradient along a rostro-caudal axis. In particular, we found 1) a rostral subregion functionally connected with prefrontal cortex, which likely supports high-level cognitive processes, such as working memory, 2) a central subregion showing a mixed behavioral profile and functional connectivity to parietal regions of the dorsal attention network, and 3) a caudal subregion closely integrated with the motor system. Additionally, we found 4) a dorsal subregion, preferentially related to hand movements and connected to both cognitive and motor regions, and 5) a ventral subregion, whose functional profile fits the concept of an eye movement-related field. In conclusion, right PMd may be considered as a functional mosaic formed by 5 subregions.

Indexed as

Brain MappingHumansMagnetic Resonance ImagingMotor CortexNeural PathwaysRestactivation likelihood estimationclusteringfunctional connectivityparcellationpremotor cortex

Identifiers

PMID26965906
PMCPMC5963821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.