ArticleWorld journal of surgical oncology2016
Clinical, radiological, and pathological features of 33 adult unilateral thalamic gliomas.
Article in World journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pineal Region Gliomas: A Systematic Review of Clinical Features and Treatment Outcomes.Anticancer research · 2022Pooled it
- Thalamic gliomas in adults: a systematic review of clinical characteristics, treatment strategies, and survival outcomes.Journal of neuro-oncology · 2021Pooled it
- Survival analysis of adult midline-located gliomas and diffuse midline gliomas: beyond the H3K27 mutation paradigm.Journal of neuro-oncology · 2026Article
- Thalamic involvement in glioblastoma is associated with lower risk of seizures: a retrospective cohort study.Journal of neuro-oncology · 2026Article
- Thalamic gliomas: A systematic review and meta-analysis.Surgical neurology international · 2026Review
- Clinico-radiological analysis and outcomes of management of thalamic space-occupying lesions: A three-year retrospective case series.Pakistan journal of medical sciences · 2025Article
- The impact of maximized resection and standardized systemic therapy on overall survival in adult patients with thalamic gliomas.Frontiers in oncology · 2025Article
- High-Grade Thalamic Glioma: Case Report with Literature Review.Medicina (Kaunas, Lithuania) · 2024Review
- Surgical Treatment of Paediatric Thalamic Gliomas-Single-Centre Experience.Brain sciences · 2024Article
- Long-Term Outcomes and Survival Rates of Patients Undergoing Biopsy Vs. Maximum Safe Resection for Thalamic Lesions: A Short Review on Current Evidence.Galen medical journal · 2024Review
- Assessment the neurodegenaration process of post-geniculate optic pathway in thalamic tumors using optical coherence tomography: Post-geniculate optic pathway in thalamic tumors.International ophthalmology · 2023Article
- Abrupt Cognitive Decline in Thalamic Tumor-Case Report.Indian journal of psychological medicine · 2023Article
- Article
- Risk Factors for Early Hydrocephalus on Post Unilateral Thalamic Tumor Resection.Frontiers in surgery · 2022Article
- Evolution of surgical attitudes to paediatric thalamic tumours: the alder hey experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- The concept of "Four Walls, Two Poles" in the lesions of the thalamus and ganglion regions: case report and literature review.BMC surgery · 2021Review
- Lesion covariance networks reveal proposed origins and pathways of diffuse gliomas.Brain communications · 2021Article
- Adult H3K27M-mutant diffuse midline glioma with gliomatosis cerebri growth pattern: Case report and review of the literature.International journal of surgery case reports · 2020Article
- In Reply: Thalamic Glioblastoma: Clinical Presentation, Management Strategies, and Outcomes.Neurosurgery · 2019Article
- Distant recurrences limit the survival of patients with thalamic high-grade gliomas after successful resection.Neurosurgical review · 2017Article
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Authors and funding
10 authors.
Funding
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Abstract
backgroundUnilateral adult thalamic gliomas are rarely reported. In this study, the authors aimed to analyze the clinical, radiological, and pathological features of adult primary unilateral thalamus gliomas (UTGs).
methodsClinical data of 33 UTGs in adults who underwent surgical treatment between 2005 and 2014 at the Beijing Tiantan Hospital were collected and retrospectively studied. Follow-up evaluation was performed.
resultsThis study included 21 males and 12 females with a mean age of 43.1 years. The most common symptoms were headache (75.8%, 25/33 patients) and motor deficits (42.4%, 14/33 patients). Radiological results showed that enhancement was common (90.9%, 30/33 patients) and included cystic appearances in 9 cases (27.3%). All patients underwent maximal safe tumor resection. Gross total resection (GTR) was achieved in 19 cases, subtotal resection (≥80%) in 9 cases, and partial resection (<80%) in 5 cases. Molecular pathology results were available in 15 cases. After surgery, 25 patients received postoperative adjuvant therapy based on the remaining pathology. The median follow-up period of all 33 patients with UTGs was 17 months (1 week~49 months). Twenty-four patients experienced tumor recurrence. The 1-year and 2-year progression-free survival (PFS) rates were 49.0 and 10.2%, respectively. The 1-year and 2-year overall survival (OS) rates were 68.1 and 25.9%, respectively. Survival analyses revealed that several predictive factors were correlated with better prognosis, among which, GTR and tumor with cystic appearances were significantly associated with a longer survival.
conclusionsAdult UTGs displayed a wide spectrum of clinical features. GTR can be achieved in adult UTGs with acceptable complications and conferred a better prognosis. Tumor with cystic appearance may indicate better prognosis. More patients and longer follow-up periods are needed to further elucidate the biological features of adult UTGs.
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