Evidence map›Paper›PMID 26964062›Full record

ArticlePLoS pathogens2016

The Herpes Simplex Virus Neurovirulence Factor γ34.5: Revealing Virus-Host Interactions.

Douglas R Wilcox, Richard Longnecker

Abstract read
In one paragraph

Article in PLoS pathogens, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Neurovirulent Pathogens Across the Human Lifespan: A Balancing Act.Journal of the Pediatric Infectious Diseases Society · 2025
    Article
  12. Review
  13. Article
  14. Cell and gene therapy in neuro-oncology.Handbook of clinical neurology · 2024
    Review
  15. Article
  16. OncoVEXJournal for immunotherapy of cancer · 2023
    Article
  17. Gene Therapy for High Grade Glioma: The Clinical Experience.Expert opinion on biological therapy · 2023
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Douglas R WilcoxDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Richard LongneckerDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008152 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARDEHALI, HOSSEIN · 1987 to 2021
$24.0M
HERPESVIRUS GENE EXPRESSION IN TRANSFORMED CELLSR01CA021776 · NCI · UNIVERSITY OF CHICAGO · PI LONGNECKER, RICHARD M · 1985 to 2017
$4.2M
Training Program in Viral ReplicationT32AI060523 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LAIMINS, LAIMONIS A. · 2004 to 2013
$1.4M
A Development-Specific Mechanism of Pathogenesis in HSV EncephalitisF30AI116106 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WILCOX, DOUGLAS ROBERT · 2015 to 2017
$134k
NCI NIH HHS P30 CA060553NCI NIH HHS R01 CA021776NCI NIH HHS R01CA021776NIAID NIH HHS F30 AI116106NIAID NIH HHS F30AI116106NIAID NIH HHS T32 AI060523NIAID NIH HHS T32AI060523NIGMS NIH HHS T32 GM008152
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Host-Pathogen InteractionsAutophagyHerpesvirus 1, HumanHerpesvirus 2, HumanHumansMutationOncolytic VirotherapyProtein Synthesis InhibitorsViral Proteinsgamma 34.5 protein, Human herpesvirus 1ICP34.5 protein, human herpesvirus-2Protein Synthesis InhibitorsViral Proteins

Identifiers

PMID26964062
PMCPMC4786305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.