ArticlePloS one2016
Varicella-Zoster Virus in Perth, Western Australia: Seasonality and Reactivation.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Impact of natural and socio-economic factors on varicella incidence in children in Shanghai, 2013-2022.Frontiers in public health · 2025Article
- A time series study of the association between extreme temperature and ozone on varicella incidence.Scientific reports · 2024Article
- Association between Meteorological Factors and Outpatient Visits for Herpes Zoster in Hefei, China: A Time-Series Analysis.International journal of environmental research and public health · 2023Article
- Meningitis/meningoencephalitis caused by varicella zoster virus reactivation: a retrospective single-center case series study.American journal of translational research · 2022Article
- Seasonality of herpes zoster and herpes zoster ophthalmicus.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020Article
- Ultraviolet Radiation Exposure and the Risk of Herpes Zoster in Three Prospective Cohort Studies.Mayo Clinic proceedings · 2020Article
- Are there differences in immune responses following delivery of vaccines through acutely or chronically sun-exposed compared with sun-unexposed skin?Immunology · 2020Review
- Photoimmunology: how ultraviolet radiation affects the immune system.Nature reviews. Immunology · 2019Review
- Elevation of ambient temperature is associated with an increased risk of herpes zoster: a time-series analysis.Scientific reports · 2019Article
- The impact of childhood varicella vaccination on the incidence of herpes zoster in the general population: modelling the effect of exogenous and endogenous varicella-zoster virus immunity boosting.BMC infectious diseases · 2019Article
- Monitoring Interest in Herpes Zoster Vaccination: Analysis of Google Search Data.JMIR public health and surveillance · 2018Article
- Environmental effects of ozone depletion and its interactions with climate change: Progress report, 2016.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2017Article
- Seasonality of Acute Retinal Necrosis.Journal of ophthalmic & vision researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentification of the factors affecting reactivation of varicella-zoster virus (VZV) largely remains an open question. Exposure to solar ultra violet (UV) radiation is speculated to facilitate reactivation. Should the role of UV in reactivation be significant, VZV reactivation patterns would generally be expected to be synchronous with seasonal UV profiles in temperate climates.
methodsWe analysed age and gender specific VZV notification time series data from Perth, Western Australia (WA). This city has more daily sunshine hours than any other major Australian city. Using the cosinor and generalized linear models, we tested these data for seasonality and correlation with UV and temperature.
resultsWe established significant seasonality of varicella notifications and showed that while herpes-zoster (HZ) was not seasonal it had a more stable seasonal component in males over 60 than in any other subpopulation tested. We also detected significant association between HZ notifications and UV for the entire Perth population as well as for females and males separately. In most cases, temperature proved to be a significant factor as well.
conclusionsOur findings suggest that UV radiation may be important for VZV reactivation, under the assumption that notification data represent an acceptably accurate qualitative measure of true VZV incidence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.