ArticleGlobal public health
'I am not a man': Trans-specific barriers and facilitators to PrEP acceptability among transgender women.
Article in Global public health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
180 citing papers in PubMed, 7 syntheses or guidelines pooled it, 281 citations in OpenAlex.
- Barriers and Facilitators Influencing PrEP Uptake Among Men Who Have Sex with Men and Transgender Women in the United States: A Systematic Review.AIDS and behavior · 2026Pooled it
- A Systematic Review and Narrative Synthesis of Factors Affecting Pre-exposure Prophylaxis Willingness Among Black Women for HIV Prevention.AIDS and behavior · 2025Pooled it
- Barriers and Facilitators to HIV Pre-Exposure Prophylaxis Uptake, Adherence, and Persistence Among Transgender Populations in the United States: A Systematic Review.AIDS patient care and STDs · 2022Pooled it
- The worldwide burden of HIV in transgender individuals: An updated systematic review and meta-analysis.PloS one · 2021Pooled it
- Current research gaps: a global systematic review of HIV and sexually transmissible infections among transgender populations.Sexual health · 2017Pooled it
- Global Epidemiology of HIV Infection and Related Syndemics Affecting Transgender People.Journal of acquired immune deficiency syndromes (1999) · 2016Pooled it
- The barriers and enablers to accessing sexual health and sexual well-being services for midlife women (aged 40-65 years) in high-income countries: A mixed-methods systematic review.Women's health (London, England)Pooled it
- No significant drug-drug interaction between oral TAF-based PrEP and feminizing hormone therapy among transgender women in Thailand: the iFACT-3 study.Journal of the International AIDS Society · 2025Trial
- Exploring potential drug-drug interactions between masculinizing hormone therapy and oral pre-exposure prophylaxis (F/TDF and F/TAF) among transgender men (iMACT study): a randomized, open-label pharmacokinetic study in Thailand.Journal of the International AIDS Society · 2025Trial
- Estradiol and Spironolactone Plasma Pharmacokinetics Among Brazilian Transgender Women Using HIV Pre-Exposure Prophylaxis: Analysis of Potential Interactions.Clinical pharmacokinetics · 2023Trial
- TransPrEP: Results from the Pilot Study of a Social Network-Based Intervention to Support PrEP Adherence Among Transgender Women in Lima, Peru.AIDS and behavior · 2021Trial
- Baseline Characteristics Explain Differences in Effectiveness of Randomization to Daily Oral TDF/FTC PrEP Between Transgender Women and Cisgender Men Who Have Sex With Men in the iPrEx Trial.Journal of acquired immune deficiency syndromes (1999) · 2019Trial
- HIV pre-exposure prophylaxis in transgender women: a subgroup analysis of the iPrEx trial.The lancet. HIV · 2015Trial
- PrEP Use and Willingness Cascades Among Transgender Women in 11 Asian Countries: Findings From the PrEP APPEAL Cross-Sectional Online Survey.Journal of the International AIDS Society · 2026Article
- Perspectives on PrEP/PEP Integration in Telehealth Gender-Affirming Care: A Survey of Clients From a National Telehealth Platform.Open forum infectious diseases · 2026Article
- A Decade of Improvement and Signs of Decline in PrEP Awareness and Use in Young Trans Women.AIDS and behavior · 2026Article
- Health equity and medical mistrust: a mixed-methods analysis of medical and social determinants among transgender women of colour in the TURNNT cohort study.Culture, health & sexuality · 2026Article
- Characterising individuals with newly diagnosed HIV before versus during the era of PrEP: a descriptive time-series analysis of data from a sexual health centre in Amsterdam, the Netherlands, 2015 to 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Article
- Correlates of pre-exposure prophylaxis amongst transgender women of color taking gender-affirming hormone therapy: Findings from the TURNNT cohort study.International journal of transgender health · 2026Article
- Integrating CBPR and Implementation Science to Develop a PrEP-Promotion Intervention for Black Transgender Women.Health education & behavior : the official publication of the Society for Public Health Education · 2026Article
120 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
The frequent conflation of transgender ('trans') women with 'men who have sex with men (MSM)' in HIV prevention obscures trans women's unique gender identities, social and behavioural vulnerabilities, and their disproportionately high rates of HIV infection. Pre-exposure prophylaxis (PrEP) is an efficacious biomedical HIV prevention approach. However, trans women are underrepresented in PrEP research, and are often aggregated with MSM without consideration for their unique positions within sociocultural contexts. This study examined PrEP acceptability among trans women via three focus groups and nine individual interviews (total N = 30) in San Francisco. While knowledge of PrEP was low, interest was relatively high once participants were informed. Due to past negative healthcare experiences, ability to obtain PrEP from a trans-competent provider was cited as essential to PrEP uptake and adherence. Participants noted that PrEP could address situations in which trans women experience reduced power to negotiate safer sex, including sex work. Trans-specific barriers included lack of trans-inclusive marketing of PrEP, prioritisation of hormone use, and medical mistrust due to transphobia. Findings underscore the importance of disaggregating trans women from MSM in HIV prevention strategies to mitigate disparate risk among this highly vulnerable population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.