ReviewGut microbes2016
Bacterial species involved in the conversion of dietary flavonoids in the human gut.
Review in Gut microbes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 205 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
205 citing papers in PubMed, 1 synthesis or guideline pooled it, 492 citations in OpenAlex.
- The Impact ofCurrent neuropharmacology · 2025Pooled it
- Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections.BMC microbiology · 2021Trial
- Trial
- Article
- Research progress on the metabolic fate of citrus flavonoids and strategies to improve bioavailability.Food chemistry: X · 2026Review
- Metabolization of Flavan-3-ol Oligomers by Eggerthella lenta, a Human Gut Bacterium.Molecular nutrition & food research · 2026Article
- Kaempferol: advances in biosynthesis, molecular mechanisms, and therapeutic applications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Metabolic Profile and Dynamic Characteristics of Ziziphi Spinosae Semen Flavonoids During Biotransformation and Their Effect on Human Gut Microbiota In Vitro.Foods (Basel, Switzerland) · 2026Article
- The Intestinal Fate of Phenolic Substances in Honey: Metabolism by Gut Microbiota, Regulation of Bioavailability, and Its Prebiotic Effects on Host Health.Foods (Basel, Switzerland) · 2026Review
- Barley sprouts as a modulator of the gut microbiota, influencing glucose and lipid metabolism in ovariectomized female rats fed a high-fat diet.Nutrition research and practice · 2026Article
- Hypocholesterolemic agents and the gut microbiota: a review of interactions and modulatory activity.Pharmacological reports : PR · 2026Review
- Gut Microbial Metabotypes Shape Polyphenol Bioactivity: Toward Precision Nutrition Strategies for Human Health.Nutrients · 2026Review
- Article
- Young Barley (Molecules (Basel, Switzerland) · 2026Review
- The In Vivo Existence Forms of Engeletin and Their Anti-Hyperuricemia Activity.International journal of molecular sciences · 2026Article
- Gut Microbiota-Mediated Modulation of Intestinal Serotonin by Tea Polyphenols: Potential Mechanisms and Implications for Metabolic Health.Nutrients · 2026Review
- In Vitro Fermentation of Green Tea by Human Gut Microbiota Enhances Bioactivity and Bidirectionally Modulates Polyphenol Metabolites and Gut Microbiota.Foods (Basel, Switzerland) · 2026Article
- Red Grape Pomace as a Valuable Source of Biomolecules With Inhibitory Effect on Pro-Inflammatory and Metabolic Syndrome-Associated Enzymes: Eco-Friendly Extraction and Mechanism of Inhibition.Food science & nutrition · 2026Article
- Functional remodeling of the gut microbiome and metabolome in primary idiopathic male infertility.BMC microbiology · 2026Article
- The gut microbiome axis: how Lactobacillus-fermented soymilk orchestrates health.Archives of microbiology · 2026Review
145 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gut microbiota plays a crucial role in the conversion of dietary flavonoids and thereby affects their health-promoting effects in the human host. The identification of the bacteria involved in intestinal flavonoid conversion has gained increasing interest. This review summarizes available information on the so far identified human intestinal flavonoid-converting bacterial species and strains as well as their enzymes catalyzing the underlying reactions. The majority of described species involved in flavonoid transformation are capable of carrying out the O-deglycosylation of flavonoids. Other bacteria cleave the less common flavonoid-C-glucosides and/or further degrade the aglycones of flavonols, flavanonols, flavones, flavanones, dihydrochalcones, isoflavones and monomeric flavan-3-ols. To increase the currently limited knowledge in this field, identification of flavonoid-converting bacteria should be continued using culture-dependent screening or isolation procedures and molecular approaches based on sequence information of the involved enzymes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.