Trial reportPloS one2016
Unraveling the Relationship between Motor Symptoms, Affective States and Contextual Factors in Parkinson's Disease: A Feasibility Study of the Experience Sampling Method.
Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03435991 ('The Experience Sampling Method), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
'The Experience Sampling Method (ESM): a Real-time Patient-Reported Outcome Measure for Symptom Assessment in Patients With Overactive Bladder Syndrome.'
Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- A smartphone sensor-based digital outcome assessment of multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2022Trial
- Ecological Momentary Assessment of Daily Activities in Individuals With Neurological Disorders: Scoping Review.JMIR rehabilitation and assistive technologies · 2026Review
- Perspective: Depression in Persons with Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Use of the experience sampling method in adolescents with Duchenne muscular dystrophy: a feasibility study.European child & adolescent psychiatry · 2024Article
- The DizzyQuest Combined with Accelerometry: Daily Physical Activities and Limitations among Patients with Bilateral Vestibulopathy Due to DFNA9.Journal of clinical medicine · 2024Article
- Article
- Stress Detection Using Experience Sampling: A Systematic Mapping Study.International journal of environmental research and public health · 2022Article
- Introducing the DizzyQuest: an app-based diary for vestibular disorders.Journal of neurology · 2020Article
- Usability of the Experience Sampling Method in Parkinson's Disease on a Group and Individual Level.Movement disorders : official journal of the Movement Disorder Society · 2020Article
- Mobile Health Daily Life Monitoring for Parkinson Disease: Development and Validation of Ecological Momentary Assessments.JMIR mHealth and uHealth · 2020Observational
- Monitoring Parkinson's disease symptoms during daily life: a feasibility study.NPJ Parkinson's disease · 2019Article
- An update on adaptive deep brain stimulation in Parkinson's disease.Movement disorders : official journal of the Movement Disorder Society · 2018Review
- Evaluation of smartphone-based testing to generate exploratory outcome measures in a phase 1 Parkinson's disease clinical trial.Movement disorders : official journal of the Movement Disorder Society · 2018Article
- Clinical Markers of Anxiety Subtypes in Parkinson Disease.Journal of geriatric psychiatry and neurology · 2018Article
- Clinician and patient perspectives on meaningful Parkinson's disease impacts for digital assessment.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Parkinson's disease (PD), the complex relationship between motor symptoms, affective states, and contextual factors remains to be elucidated. The Experience Sampling Method provides (ESM) a novel approach to this issue. Using a mobile device with a special purpose application (app), motor symptoms, affective states and contextual factors are assessed repeatedly at random moments in the flow of daily life, yielding an intensive time series of symptoms and experience. The aim of this study was to study the feasibility of this method.
methodWe studied the feasibility of a five-day period of ESM in PD and its ability to objectify diurnal fluctuations in motor symptom severity and their relation with affect and contextual factors in five PD patients with motor fluctuations.
resultsParticipants achieved a high compliance, with 84% of assessment moments completed without disturbance of daily activities. The utility of the device was rated 8 on a 10-point scale. We were able to capture extensive diurnal fluctuations that were not revealed by routine clinical assessment. In addition, we were able to detect clinically relevant associations between motor symptoms, emotional fluctuations and contextual factors at an intra-individual level.
conclusionsESM represents a viable and novel approach to elucidate relationships between motor symptoms, affective states and contextual factors at the level of individual subjects. ESM holds promise for clinical practice and scientific research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.