Evidence map›Paper›PMID 26962808›Full record

Trial reportMedicine2016

Pancreatic Stent or Rectal Indomethacin-Which Better Prevents Post-ERCP Pancreatitis?: A Propensity Score Matching Analysis.

Guo-Dong Li, Xin-Yong Jia, Hai-Yan Dong, Qiu-Ping Pang, Hai-Lan Zhai, Xiu-Juan Zhang, Rong Guo, Yan-Chun Dong, Cheng-Yong Qin

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Preventing Post-ERCP Pancreatitis: Update 2016.Current treatment options in gastroenterology · 2016
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guo-Dong LiFrom the Department of Endoscopy, Shandong Provincial Qianfoshan Hospital, Shandong University (G-DL, X-YJ, H-YD, Q-PP, HLZ, X-JZ, RG, Y-CD), and Department of Gastroenterology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China (C-YQ).
Xin-Yong Jia
Hai-Yan Dong
Qiu-Ping Pang
Hai-Lan Zhai
Xiu-Juan Zhang
Rong Guo
Yan-Chun Dong
Cheng-Yong Qin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated and compared 2 clinical strategies to prevent postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).We retrospectively reviewed data from patients who underwent ERCP between 2008 and 2014. Of 623 patients at high risk for PEP, 145 were treated with prophylactic pancreatic stent placement (PSP) only, and 478 were treated with rectal indomethacin (RI) only, for PEP prevention. Patients were matched by one-to-one propensity score matching (PSM) by risk factors, with overall PEP incidence as primary outcome, and moderate or severe PEP and complication rates as secondary outcomes.Of 623 patients with high-risk factors, 145 pairs were generated after PSM. Thirty-two patients developed pancreatitis-10 (6.9 %) in the PSP group and 22 (15.2 %) in the RI group (P = 0.025). Moderate-to-severe pancreatitis developed in 5 patients (2.8%) in the PSP group and 14 patients (9.7 %) in the RI group (P = 0.047).Although indomethacin represents an easy, inexpensive treatment, prophylactic PSP is still the better prevention strategy for PEP.

Indexed as

Risk AssessmentStentsAdministration, RectalAdultAnti-Inflammatory Agents, Non-SteroidalChinaCholangiopancreatography, Endoscopic RetrogradeFemaleFollow-Up StudiesHumansIncidenceIndomethacinMalePancreatitis, Acute NecrotizingPostoperative ComplicationsPractice Guidelines as TopicAnti-Inflammatory Agents, Non-SteroidalIndomethacin

Identifiers

PMID26962808
PMCPMC4998889

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.