ArticleThe New England journal of medicine2016
Survival Benefit with Kidney Transplants from HLA-Incompatible Live Donors.
Registry-linked trialOpen access · bronzeAbstract readMulticenter Study
In one paragraph
Article in The New England journal of medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05431712 (Impact of Donor-Specific Antibodies in), which is not on this map. Cited by 160 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
160citing papers in PubMed, 3 pooled it
36.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Donor-Specific Antibodies in (Highly-) Immunized Living Donor Kidney Transplant Recipients
Who cites it
160 citing papers in PubMed, 3 syntheses or guidelines pooled it, 347 citations in OpenAlex.
- Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach From the Writing Committee of the American Society for Apheresis: The Tenth Special Issue.Journal of clinical apheresis · 2026Guideline
- European Guideline for the Management of Kidney Transplant Patients With HLA Antibodies: By the European Society for Organ Transplantation Working Group.Transplant international : official journal of the European Society for Organ Transplantation · 2022Guideline
- KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors.Transplantation · 2017Guideline
- Five Years Follow-up of Imlifidase Desensitized Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2025Trial
- Immunoadsorption-Based HLA Desensitization in Patients Awaiting Deceased Donor Kidney Transplantation: An Interventional, Non-Randomised, Single Cohort Study.Transplant international : official journal of the European Society for Organ Transplantation · 2023Trial
- Outcomes at 3 years posttransplant in imlifidase-desensitized kidney transplant patients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Trial
- Imlifidase Desensitization in Crossmatch-positive, Highly Sensitized Kidney Transplant Recipients: Results of an International Phase 2 Trial (Highdes).Transplantation · 2021Trial
- Safety and efficacy of eculizumab in the prevention of antibody-mediated rejection in living-donor kidney transplant recipients requiring desensitization therapy: A randomized trial.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Trial
- Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti-HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018Trial
- Characteristics of compatible pair participants in kidney paired donation at a single center.Clinical transplantation · 2017Trial
- B cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapy.Journal of translational medicine · 2017Trial
- Acceptability of an open-label wait-listed trial design: Experiences from the PROUD PrEP study.PloS one · 2017Trial
- ISOT Position Statement on Immunological Evaluation in Kidney Transplantation.Clinical transplantation · 2026Article
- Clinical implications of imlifidase interference in antibody screening and transfusion management.Transfusion · 2026Article
- Review
- Clinical and immunological predictors of receiving deceased donor kidney transplantation and waitlist dropout: a single-center study in Japan.Clinical and experimental nephrology · 2026Article
- Impact of Cold Ischemia Time on Allograft Survival and Policy.Kidney international reports · 2026Article
- Sensitization and Deceased-Donor Kidney Transplant Access in France.Kidney international reports · 2026Article
- Clinical outcomes of bortezomib-based desensitization in highly sensitized living and deceased donor kidney transplantation.Kidney research and clinical practice · 2026Article
- Risk-adapted HLA delisting and imlifidase-enabled deceased-donor kidney transplantation in highly sensitized kidney transplant candidates: a German expert consensus report.Frontiers in immunology · 2026Article
100 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
33 authors at 9 institutions in 1 country.
Babak J OrandiFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Xun LuoFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Allan B MassieFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Jacqueline M Garonzik-WangFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Bonne E LonzeFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Rizwan AhmedFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Kyle J Van ArendonkFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Mark D StegallFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Stanley C JordanFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Jose OberholzerFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Ty B DunnFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Lloyd E RatnerFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Sandip KapurFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Ronald P PelletierFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
John P RobertsFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Marc L MelcherFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Pooja SinghFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Debra L SudanFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Marc P PosnerFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Jose M El-AmmFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Ron ShapiroFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Matthew CooperFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
George S LipkowitzFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Michael A ReesFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Christopher L MarshFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Bashir R SankariFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
David A GerberFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Paul W NelsonFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Jason WellenFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Adel BozorgzadehFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
A Osama GaberFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Robert A MontgomeryFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
Dorry L SegevFrom the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore (B.J.O., X.L., A.B.M., B.E.L., R.A., K.J.V.A., R.A.M., D.L. Segev); the Department of Surgery, Barnes-Jewish Hospital, St. Louis (J.M.G.-W., J.W.); the Department of Surgery, Mayo Clinic, Rochester (M.D.S.), and the Department of Surgery, University of Minnesota, Minneapolis (T.B.D.) - both in Minnesota; the Department of Medicine, Cedars-Sinai Comprehensive Transplant Center, Los Angeles (S.C.J.), the Department of Surgery, University of California,San Francisco, San Francisco (J.P.R.), the Department of Surgery, Stanford University, Palo Alto (M.L.M.), and the Department of Surgery, Scripps Clinic and Green Hospital, La Jolla (C.L.M.) - all in California; the Department of Surgery, University of Illinois-Chicago, Chicago (J.O.); the Department of Surgery, Columbia University Medical Center (L.E.R.), and the Department of Surgery, New York Presbyterian-Weill Cornell Medical Center (S.K.) - both in New York; the Department of Surgery, Ohio State University, Columbus (R.P.P.), the Department of Urology, University of Toledo Medical Center, Toledo (M.A.R.), and the Department of Urology, Cleveland Clinic, Cleveland (B.R.S.) - all in Ohio; the Department of Medicine, Thomas Jefferson University Hospital, Philadelphia (P.S.); the Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh (R.S.); the Department of Surgery, Duke University Medical Center, Durham (D.L. Sudan), and the Department of Surgery, University of North Carolina School of Medicine, Chapel Hill (D.A.G.) - both in North Carolina; the Department of Surgery, Virginia Commonwealth University, Richmond (M.P.P.); Integris Baptist Medical Center, Transplant Division, Oklahoma City (J.M.E.-A.); Medstar Georgetown Transplant Institute, Washington, DC (M.C.); the Department of Surgery, Baystate Medical Center, Springfield (G.S.L.), and the Department of Surgery, University of Massachusetts Memorial Medical Ce
University of Illinois Chicago · USJohns Hopkins University · USJewish Hospital · USCornell University · USBarnes-Jewish Hospital · USBaystate Medical Center · USColumbia University Irving Medical Center · USJohns Hopkins Medicine · USMethodist Hospital · US
Funding
Quantifying Risk And Survival Benefit from Incompatible Kidney TransplantationR01DK098431 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2013 to 2017
$3.7MDevelopment of a National Incompatible Kidney Transplant RegistryRC1DK086731 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MONTGOMERY, ROBERT A · 2009 to 2010
$998kPatient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922kQuantifying Risk and Survival Benefit from Incompatible Kidney TransplantationF32DK093218 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ORANDI, BABAK JOHN · 2011 to 2014
$185kNIDDK NIH HHS F32 DK093218NIDDK NIH HHS F32DK093218NIDDK NIH HHS K24 DK101828NIDDK NIH HHS K24DK10182801NIDDK NIH HHS R01 DK098431NIDDK NIH HHS R01DK098431NIDDK NIH HHS RC1 DK086731NIDDK NIH HHS RC1DK086731
Abstract
backgroundA report from a high-volume single center indicated a survival benefit of receiving a kidney transplant from an HLA-incompatible live donor as compared with remaining on the waiting list, whether or not a kidney from a deceased donor was received. The generalizability of that finding is unclear.
methodsIn a 22-center study, we estimated the survival benefit for 1025 recipients of kidney transplants from HLA-incompatible live donors who were matched with controls who remained on the waiting list or received a transplant from a deceased donor (waiting-list-or-transplant control group) and controls who remained on the waiting list but did not receive a transplant (waiting-list-only control group). We analyzed the data with and without patients from the highest-volume center in the study.
resultsRecipients of kidney transplants from incompatible live donors had a higher survival rate than either control group at 1 year (95.0%, vs. 94.0% for the waiting-list-or-transplant control group and 89.6% for the waiting-list-only control group), 3 years (91.7% vs. 83.6% and 72.7%, respectively), 5 years (86.0% vs. 74.4% and 59.2%), and 8 years (76.5% vs. 62.9% and 43.9%) (P<0.001 for all comparisons with the two control groups). The survival benefit was significant at 8 years across all levels of donor-specific antibody: 89.2% for recipients of kidney transplants from incompatible live donors who had a positive Luminex assay for anti-HLA antibody but a negative flow-cytometric cross-match versus 65.0% for the waiting-list-or-transplant control group and 47.1% for the waiting-list-only control group; 76.3% for recipients with a positive flow-cytometric cross-match but a negative cytotoxic cross-match versus 63.3% and 43.0% in the two control groups, respectively; and 71.0% for recipients with a positive cytotoxic cross-match versus 61.5% and 43.7%, respectively. The findings did not change when patients from the highest-volume center were excluded.
conclusionsThis multicenter study validated single-center evidence that patients who received kidney transplants from HLA-incompatible live donors had a substantial survival benefit as compared with patients who did not undergo transplantation and those who waited for transplants from deceased donors. (Funded by the National Institute of Diabetes and Digestive and Kidney Diseases.).
Indexed as
HistocompatibilityKidney TransplantationLiving DonorsGraft SurvivalHistocompatibility TestingHLA AntigensHumansSurvival AnalysisTissue and Organ ProcurementWaiting ListsHLA Antigens
Identifiers
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NCT05431712ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.