Evidence map›Paper›PMID 26962430›Full record

ArticleMedChemComm2015

Discovery of pyridyl-based inhibitors of

Zhiyong Yu, James A Brannigan, Kaveri Rangachari, William P Heal, Anthony J Wilkinson, Anthony A Holder, Robin J Leatherbarrow, Edward W Tate

Open access · hybridAbstract read
In one paragraph

Article in MedChemComm, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2025
    Review
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  3. Exploring Subsite Selectivity withinJournal of medicinal chemistry · 2024
    Article
  4. Article
  5. Article
  6. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Zhiyong YuDepartment of Chemistry , Imperial College London , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0)2075 943 752.
James A BranniganYork Structural Biology Laboratory , Department of Chemistry , University of York , York , YO10 5DD , UK.
Kaveri RangachariThe Francis Crick Institute , Mill Hill Laboratory , The Ridgeway , London , NW7 1AA , UK.
William P HealDepartment of Chemistry , Imperial College London , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0)2075 943 752.
Anthony J WilkinsonYork Structural Biology Laboratory , Department of Chemistry , University of York , York , YO10 5DD , UK.
Anthony A HolderThe Francis Crick Institute , Mill Hill Laboratory , The Ridgeway , London , NW7 1AA , UK.
Robin J LeatherbarrowDepartment of Chemistry , Imperial College London , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0)2075 943 752.
Edward W TateDepartment of Chemistry , Imperial College London , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0)2075 943 752.
Imperial College London · GBTransnational Press LondonUniversity of York · GBThe Francis Crick Institute · GB

Funding

Medical Research Council 0900278Medical Research Council G0900278Medical Research Council U117532067Wellcome Trust 087792
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID26962430
PMCPMC4757856
OpenAlexW1810905971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.