Evidence map›Paper›PMID 26962429›Full record

ArticleMedChemComm2015

Discovery of high affinity inhibitors of

Mark D Rackham, Zhiyong Yu, James A Brannigan, William P Heal, Daniel Paape, K Victoria Barker, Anthony J Wilkinson, Deborah F Smith, Robin J Leatherbarrow, Edward W Tate

Open access · hybridAbstract read
In one paragraph

Article in MedChemComm, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. ACS medicinal chemistry letters · 2026
    Article
  2. Molecules (Basel, Switzerland) · 2025
    Review
  3. Frontiers in pharmacology · 2025
    Article
  4. Identification of PotentialMetabolites · 2023
    Article
  5. Article
  6. Screening of medicinal plants unraveled the leishmanicidal credibility ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  7. Review
  8. Novel Thienopyrimidine Inhibitors ofJournal of medicinal chemistry · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Mark D RackhamDepartment of Chemistry , Imperial College London , South Kensington Campus , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0) 2075 943752.
Zhiyong YuDepartment of Chemistry , Imperial College London , South Kensington Campus , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0) 2075 943752.
James A BranniganStructural Biology Laboratory , Department of Chemistry , University of York , York , YO10 5DD , UK.
William P HealDepartment of Chemistry , Imperial College London , South Kensington Campus , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0) 2075 943752.
Daniel PaapeDepartment of Biology , University of York , York , YO10 5DD , UK.
K Victoria BarkerDepartment of Chemistry , Imperial College London , South Kensington Campus , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0) 2075 943752.
Anthony J WilkinsonStructural Biology Laboratory , Department of Chemistry , University of York , York , YO10 5DD , UK.
Deborah F SmithDepartment of Biology , University of York , York , YO10 5DD , UK.
Robin J LeatherbarrowDepartment of Chemistry , Imperial College London , South Kensington Campus , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0) 2075 943752.
Edward W TateDepartment of Chemistry , Imperial College London , South Kensington Campus , London , SW7 2AZ , UK . Email: e.tate@imperial.ac.uk ; Tel: +44 (0) 2075 943752.
University of York · GBImperial College London · GBKensington Health · CATransnational Press London

Funding

Medical Research Council 0900278Medical Research Council U117532067Wellcome Trust 087792
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID26962429
PMCPMC4757855
OpenAlexW1766553222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.