Evidence map›Paper›PMID 26962200›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2016

Racial Patterns of Peripheral T-Cell Lymphoma Incidence and Survival in the United States.

Scott V Adams, Polly A Newcomb, Andrei R Shustov

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 3 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 130 citations in OpenAlex.

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  14. Epidemiology of mature T-cell and NK-cell neoplasms: east and west.The Lancet regional health. Western Pacific · 2025
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Scott V AdamsScott V. Adams and Polly A. Newcomb, Fred Hutchinson Cancer Research Center; and Andrei R. Shustov, University of Washington School of Medicine, Seattle, WA.
Polly A NewcombScott V. Adams and Polly A. Newcomb, Fred Hutchinson Cancer Research Center; and Andrei R. Shustov, University of Washington School of Medicine, Seattle, WA.
Andrei R ShustovScott V. Adams and Polly A. Newcomb, Fred Hutchinson Cancer Research Center; and Andrei R. Shustov, University of Washington School of Medicine, Seattle, WA. ashustov@seattlecca.org.
Fred Hutch Cancer Center · USUniversity of Washington · US

Funding

Training and Research in Colon Cancer SurvivalK05CA152715 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI NEWCOMB, POLLY A · 2010 to 2019
$991k
NCI NIH HHS K05 CA152715
6 · The paper itself

Abstract

purposeTo compare incidence and survival of peripheral T-cell lymphoma (PTCL) subtypes among US racial/ethnic groups.

methodsPatients with PTCL (age ≥ 15 years; 2000 to 2012) were identified in the Surveillance, Epidemiology, and End Results (SEER) registries. Race/ethnicity was categorized as non-Hispanic white, black, Asian/Pacific Islander, Hispanic white, or American Indian/Alaskan native. Age-standardized annual incidence rates and incidence rate ratios were estimated with 95% CIs, and case-case odds ratios were estimated by race/ethnicity using polytomous regression. Survival was estimated from SEER follow-up data with Cox regression.

resultsThirteen thousand one hundred seven patients with PTCL were identified. Annual PTCL incidence was highest in blacks and lowest in Native Americans. Compared with non-Hispanic whites, blacks had a higher incidence of PTCL not otherwise specified (PTCL-NOS), anaplastic large-cell lymphoma, and adult T-cell leukemia/lymphoma (ATLL) and a lower incidence of angioimmunoblastic T-cell lymphoma (AITL); Asians/Pacific Islanders had a higher incidence of AITL, extranodal nasal-type natural killer/T-cell lymphoma and NK-cell leukemia (ENKCL), and ATLL and a lower incidence of anaplastic large-cell lymphoma; Hispanics had a higher incidence of AITL and ENKCL; and Native Americans had a lower incidence of PTCL-NOS (all P < .05). The ratio of ENKCL to PCTL-NOS among Native Americans, Asians/Pacific Islanders, and Hispanic whites was approximately three- to four-fold the same ratio among non-Hispanic whites. Survival varied significantly by race/ethnicity (P < .001), with blacks in particular experiencing shorter survival for most subtypes.

conclusionStriking variation in incidence, proportions of PTCL subtypes, and survival was observed. Aspects of these PTCL subtype patterns, such as for ENKCL and ATLL, were similar to corresponding global populations. Despite the small population size and limited number of Native American patients, PTCL subtype frequencies in this group were distinct but most similar to Hispanic whites. Survival disparities were evident, especially for blacks compared with non-Hispanic whites.

Indexed as

AgedAlaskaBlack or African AmericanBlack PeopleFemaleHispanic or LatinoHumansIncidenceIndians, North AmericanInuitLymphoma, T-Cell, PeripheralMaleMiddle AgedNative Hawaiian or Pacific IslanderSEER ProgramUnited States

Identifiers

PMID26962200
PMCPMC5070555
OpenAlexW2264394109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.