ArticleScientific reports2016
Illumina microRNA profiles reveal the involvement of miR397a in Citrus adaptation to long-term boron toxicity via modulating secondary cell-wall biosynthesis.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 51 citations in OpenAlex.
- Single-cell transcriptional profiling in Arabidopsis root exposed to boron toxicity at seedling stages.Plant molecular biology · 2025Article
- MicroRNA gatekeepers: Orchestrating rhizospheric dynamics.Journal of integrative plant biology · 2025Review
- The MdERF61-mdm-miR397b-MdLAC7b module regulates apple resistance to Fusarium solani via lignin biosynthesis.Plant physiology · 2024Article
- Integrated microRNA and whole-transcriptome sequencing reveals the involvement of small and long non-coding RNAs in the fiber growth of ramie plant.BMC genomics · 2023Article
- Identification of Competing Endogenous RNAs (ceRNAs) Network Associated with Drought Tolerance inInternational journal of molecular sciences · 2022Article
- MicroRNA Mediated Plant Responses to Nutrient Stress.International journal of molecular sciences · 2022Review
- CsiLAC4 modulates boron flow in Arabidopsis and Citrus via high-boron-dependent lignification of cell walls.The New phytologist · 2022Article
- The elemental defense effect of cadmium on Alternaria brassicicola in Brassica juncea.BMC plant biology · 2022Article
- Effect of boron toxicity on pollen tube cell wall architecture and the relationship of cell wall components ofFrontiers in plant science · 2022Article
- Review
- MicroRNAs in Woody Plants.Frontiers in plant science · 2021Review
- Illumina sequencing revealed roles of microRNAs in different aluminum tolerance of two citrus species.Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- MicroRNA comparison between poplar and larch provides insight into the different mechanism of wood formation.Plant cell reports · 2020Article
- Contributions of Adaptive Plant Architecture to Transgressive Salinity Tolerance in Recombinant Inbred Lines of Rice: Molecular Mechanisms Based on Transcriptional Networks.Frontiers in genetics · 2020Article
- miRNA-mediated regulation of auxin signaling pathway during plant development and stress responses.Journal of biosciences · 2020Review
- Identification of Appropriate Reference Genes for Normalizing miRNA Expression in Citrus Infected byGenes · 2019Article
- Identification of microRNAs and relative target genes in Moringa oleifera leaf and callus.Scientific reports · 2019Article
- MicroRNA Sequencing RevealedInternational journal of molecular sciences · 2019Article
- Analysis of the laccase gene family and miR397-/miR408-mediated posttranscriptional regulation inPeerJ · 2019Article
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms underlying tolerance to B-toxicity in plants are still controversial. Our previous studies indicated that B-toxicity is mainly limited to leaves in Citrus and that alternations of cell-wall structure in vascular bundles are involved in tolerance to B-toxicity. Here, miRNAs and their expression patterns were first identified in B-treated Citrus sinensis (tolerant) and C. grandis (intolerant) leaves via high-throughput sequencing. Candidate miRNAs were then verified with molecular and anatomical approaches. The results showed that 51 miRNAs in C. grandis and 20 miRNAs in C. sinensis were differentially expressed after B-toxic treatment. MiR395a and miR397a were the most significantly up-regulated miRNAs in B-toxic C. grandis leaves, but both were down-regulated in B-toxic C. sinensis leaves. Four auxin response factor genes and two laccase (LAC) genes were confirmed through 5'-RACE to be real targets of miR160a and miR397a, respectively. Up-regulation of LAC4 resulted in secondary deposition of cell-wall polysaccharides in vessel elements of C. sinensis, whereas down-regulation of both LAC17 and LAC4, led to poorly developed vessel elements in C. grandis. Our findings demonstrated that miR397a plays a pivotal role in woody Citrus tolerance to B-toxicity by targeting LAC17 and LAC4, both of which are responsible for secondary cell-wall synthesis.
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