ArticleScientific reports2016
Population Attributable Risk Fractions of Maternal Overweight and Obesity for Adverse Perinatal Outcomes.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Impact of preconception, pregnancy, and postpartum culinary nutrition education interventions: a systematic review.Nutrition reviews · 2021Pooled it
- Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, North American and Australian cohorts.BJOG : an international journal of obstetrics and gynaecology · 2019Pooled it
- Blood Serum From Obese Women Raises ROS Production by Neural Stem Cells.Developmental neurobiology · 2026Article
- The effect of maternal pre-pregnancy body mass index on hypertensive disorders of pregnancy (HDP): a systematic review and dose-response meta-analysis of cohort studies involving 50 million pregnancies.EClinicalMedicine · 2025Article
- Obesity and cesarean section rate among low-risk primiparous women in Victoria, Australia: A population-based study.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Article
- Reported health, social support, stress and associations with choline intake in pregnant women in central South Africa: the NuEMI study 2018-2019.Archives of public health = Archives belges de sante publique · 2023Article
- Impact of Co-Occurrence of Obesity and SARS-CoV-2 Infection during Pregnancy on Placental Pathologies and Adverse Birth Outcomes: A Systematic Review and Narrative Synthesis.Pathogens (Basel, Switzerland) · 2023Review
- Burden and Trend of Macrosomia and Large-for-Gestational-Age Neonates Attributable to High Pre-Pregnancy Body Mass Index in China, 2013-2017: A Population-Based Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2023Article
- Sex-specific effects of maternal weight loss on offspring cardiometabolic outcomes in the obese preeclamptic-like mouse model, BPH/5.Physiological reports · 2022Article
- Projected Return on Investment From Implementation of a Lifestyle Intervention to Reduce Adverse Pregnancy Outcomes.JAMA network open · 2022Article
- Trends in Prepregnancy Obesity and Association With Adverse Pregnancy Outcomes in the United States, 2013 to 2018.Journal of the American Heart Association · 2021Article
- Risk of preterm birth after prior term cesarean.BJOG : an international journal of obstetrics and gynaecology · 2020Article
- Maternal pre-pregnancy weight status and health care use for mental health conditions in the offspring.European child & adolescent psychiatry · 2019Article
- Involvement of Receptor for Advanced Glycation Endproducts in Hypertensive Disorders of Pregnancy.International journal of molecular sciences · 2019Article
- Pregnancy After Bariatric Surgery: a Comparative Study of Post-Bariatric Pregnant Women Versus Non-Bariatric Obese Pregnant Women.Obesity surgery · 2019Article
- Adverse perinatal outcomes for obese women are influenced by the presence of comorbid diabetes and hypertensive disorders.Scientific reports · 2019Article
- Lifestyle intervention strategies in early life to improve pregnancy outcomes and long-term health of offspring: a narrative review.Journal of developmental origins of health and disease · 2019Review
- Association of paternal age with perinatal outcomes between 2007 and 2016 in the United States: population based cohort study.BMJ (Clinical research ed.) · 2018Article
- Development of a Healthy Lifestyle Mobile App for Overweight Pregnant Women: Qualitative Study.JMIR mHealth and uHealth · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of the current study was to determine the proportion of adverse perinatal outcomes that could be potentially prevented if maternal obesity were to be reduced or eliminated (population attributable risk fractions, PARF); and the number needed to treat (NNT) of overweight or obese women to prevent one case of adverse perinatal outcome. Data from the Atlee Perinatal Database on 66,689 singleton infants born in Nova Scotia, Canada, between 2004 and 2014, and their mothers were used. Multivariable-adjusted PARFs and NNTs of maternal pre-pregnancy weight status were determined for various perinatal outcomes under three scenarios: If all overweight and obese women were to i) become normal weight before pregnancy; ii) shift down one weight class; or iii) lose 10% of their body weight, significant relative reductions would be seen for gestational diabetes mellitus (GDM, 57/33/15%), hypertensive disorders of pregnancy (HDP, 26/16/6%), caesarean section (CS, 18/10/3%), and large for gestational age births (LGA, 24/14/3%). The NNT were lowest for the outcomes GDM, induction of labour, CS, and LGA, where they ranged from 13 to 73. The study suggests that a substantial proportion of adverse perinatal outcomes may be preventable through reductions in maternal pre-pregnancy weight.
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Registered trials
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