Evidence map›Paper›PMID 26961383›Full record

ArticleEnvironmental health : a global access science source2016

Reducing burden of disease from residential indoor air exposures in Europe (HEALTHVENT project).

Arja Asikainen, Paolo Carrer, Stylianos Kephalopoulos, Eduardo de Oliveira Fernandes, Pawel Wargocki, Otto Hänninen

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 222 citations in OpenAlex.

  1. Indoor Exposure to Selected Air Pollutants in the Home Environment: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Global Burden of Disease from Environmental Factors.Annual review of public health · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Air pollution and health prevention: A document of reflection.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  13. Article
  14. A critical review of heating, ventilation, and air conditioning (HVAC) systems within the context of a global SARS-CoV-2 epidemic.Process safety and environmental protection : transactions of the Institution of Chemical Engineers, Part B · 2021
    Review
  15. High Levels of Fine Particulate Matter (PMInternational journal of environmental research and public health · 2021
    Article
  16. Sources of indoor PMEnvironmental research · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Arja AsikainenDepartment of Health Protection, National Institute for Health and Welfare, Neulaniementie 4, 70210, Kuopio, Finland. arja.asikainen@thl.fi.
Paolo CarrerDepartment of Occupational Health, University of Milan, Via G.B. Grassi 74, 20157, Milan, Italy. paolo.carrer@unimi.it.
Stylianos KephalopoulosEuropean Commission, Joint Research Centre, Via Enrico Fermi 2749, I - 21027, Ispra, Italy. stylianos.kephalopoulos@jrc.ec.europa.eu.
Eduardo de Oliveira FernandesUniversity of Porto, INEGI, Rua Dr. Roberto Frias, 4200 400, Porto, Portugal. eof@fe.up.pt.
Pawel WargockiTechnical University of Denmark, International Centre for Indoor Environment and Energy, DTU Civil Engineering, 2800 Kps, Lyngsby, Denmark. paw@byg.dtu.dk.
Otto HänninenDepartment of Health Protection, National Institute for Health and Welfare, Neulaniementie 4, 70210, Kuopio, Finland. otto.hanninen@thl.fi.
Finnish Institute for Health and Welfare · FIJoint Research Centre · ITTechnical University of Denmark · DKUniversidade do Porto · PTUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe annual burden of disease caused indoor air pollution, including polluted outdoor air used to ventilate indoor spaces, is estimated to correspond to a loss of over 2 million healthy life years in the European Union (EU). Based on measurements of the European Environment Agency (EEA), approximately 90 % of EU citizens live in areas where the World Health Organization (WHO) guidelines for air quality of particulate matter sized < 2.5 mm (PM2.5) are not met. Since sources of pollution reside in both indoor and outdoor air, selecting the most appropriate ventilation strategy is not a simple and straightforward task.

methodsA framework for developing European health-based ventilation guidelines was created in 2010-2013 in the EU-funded HEALTHVENT project. As a part of the project, the potential efficiency of control policies to health effects caused by residential indoor exposures of fine particulate matter (PM2.5), outdoor bioaerosols, volatile organic compounds (VOC), carbon oxide (CO) radon and dampness was estimated. The analysis was based on scenario comparison, using an outdoor-indoor mass-balance model and varying the ventilation rates. Health effects were estimated with burden of diseases (BoD) calculations taking into account asthma, cardiovascular (CV) diseases, acute toxication, respiratory infections, lung cancer and chronic obstructive pulmonary disease (COPD).

resultsThe quantitative comparison of three main policy approaches, (i) optimising ventilation rates only; (ii) filtration of outdoor air; and (iii) indoor source control, showed that all three approaches are able to provide substantial reductions in the health risks, varying from approximately 20 % to 44 %, corresponding to 400 000 and 900 000 saved healthy life years in EU-26. PM2.5 caused majority of the health effects in all included countries, but the importance of the other pollutants varied by country.

conclusionsThe present modelling shows, that combination of controlling the indoor air sources and selecting appropriate ventilation rate was the most effective to reduce health risks. If indoor sources cannot be removed or their emissions cannot be limited to an accepted level, ventilation needs to be increased to remove remaining pollutants. In these cases filtration of outdoor air may be needed to prevent increase of health risks.

Indexed as

Health Status IndicatorsAir PollutantsAir Pollution, IndoorEuropeHousingHumansModels, TheoreticalAir Pollutants

Identifiers

PMID26961383
PMCPMC4895703
OpenAlexW2293982793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.