Evidence map›Paper›PMID 26961357›Full record

ArticleGenetica2016

Comparative analysis of genome-wide Mlo gene family in Cajanus cajan and Phaseolus vulgaris.

Reena Deshmukh, V K Singh, B D Singh

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Article in Genetica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Reena DeshmukhFaculty of Science, School of Biotechnology, Banaras Hindu University, Varanasi, 221005, India.
V K SinghFaculty of Science, Centre for Bioinformatics, School of Biotechnology, Banaras Hindu University, Varanasi, 221005, India.
B D SinghFaculty of Science, School of Biotechnology, Banaras Hindu University, Varanasi, 221005, India. brahmadsingh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Mlo gene was discovered in barley because the mutant 'mlo' allele conferred broad-spectrum, non-race-specific resistance to powdery mildew caused by Blumeria graminis f. sp. hordei. The Mlo genes also play important roles in growth and development of plants, and in responses to biotic and abiotic stresses. The Mlo gene family has been characterized in several crop species, but only a single legume species, soybean (Glycine max L.), has been investigated so far. The present report describes in silico identification of 18 CcMlo and 20 PvMlo genes in the important legume crops Cajanus cajan (L.) Millsp. and Phaseolus vulgaris L., respectively. In silico analysis of gene organization, protein properties and conserved domains revealed that the C. cajan and P. vulgaris Mlo gene paralogs are more divergent from each other than from their orthologous pairs. The comparative phylogenetic analysis classified CcMlo and PvMlo genes into three major clades. A comparative analysis of CcMlo and PvMlo proteins with the G. max Mlo proteins indicated close association of one CcMlo, one PvMlo with two GmMlo genes, indicating that there was no further expansion of the Mlo gene family after the separation of these species. Thus, most of the diploid species of eudicots might be expected to contain 15-20 Mlo genes. The genes CcMlo12 and 14, and PvMlo11 and 12 are predicted to participate in powdery mildew resistance. If this prediction were verified, these genes could be targeted by TILLING or CRISPR to isolate powdery mildew resistant mutants.

Indexed as

Multigene FamilyPhylogenyAmino Acid SequenceAscomycotaCajanusDisease ResistanceGenes, PlantMolecular Sequence DataPhaseolusPlant DiseasesPlant ProteinsPlant ProteinsCajanusComputational biologyGenomicsMlo gene familyPhaseolusPhylogeny

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