Observational studyAntiviral therapy2016
Improved survival in HIV treatment programmes in Asia.
Observational study in Antiviral therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Immunological and virological response in HIV-1 infected patients receiving active antiretroviral therapy at a tertiary care center in Northern India.Iranian journal of microbiology · 2026Article
- Effectiveness and Safety of Bictegravir/Emtricitabine/Tenofovir Alafenamide in People with HIV in Korea: 24-Month Data from BICSTaR.Infection & chemotherapy · 2025Article
- Incidence of Mortality and Its Predictors Among Adult Human Immune Virus Infected Patients on Antiretroviral Therapy in Wolaita Sodo University Comprehensive Specialized Hospital, Southern Ethiopia: A Retrospective Follow-Up Study.HIV/AIDS (Auckland, N.Z.) · 2023Article
- Viral hepatitis and the cascade of care among people living with HIV in the Asia-Pacific.HIV medicine · 2022Article
- Patterns and prognosis of holding regimens for people living with HIV in Asian countries.PloS one · 2022Article
- HIV treatment outcomes among people who acquired HIV via injecting drug use in the Asia-Pacific region: a longitudinal cohort study.Journal of the International AIDS Society · 2021Observational
- Association of body mass index with immune recovery, virological failure and cardiovascular disease risk among people living with HIV.HIV medicine · 2021Article
- Observational
- Survival after long-term ART exposure: findings from an Asian patient population retained in care beyond 5 years on ART.Antiviral therapy · 2020Observational
- Treatment modification after second-line failure among people living with HIV in the Asia-Pacific.Antiviral therapy · 2020Article
- Global variations in mortality in adults after initiating antiretroviral treatment: an updated analysis of the International epidemiology Databases to Evaluate AIDS cohort collaboration.AIDS (London, England) · 2019Article
- Diabetes, mortality and glucose monitoring rates in the TREAT Asia HIV Observational Database Low Intensity Transfer (TAHOD-LITE) study.HIV medicine · 2019Observational
- Diabetes mellitus burden among people living with HIV from the Asia-Pacific region.Journal of the International AIDS Society · 2019Observational
- Patterns of detectable viraemia among children and adults with HIV infection taking antiretroviral therapy in Zimbabwe.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019Article
- Survival and associated factors among people living with HIV/AIDS: A 30-year national survey in Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Article
- Durability of antiretroviral therapy regimens and determinants for change in HIV-1-infected patients in the TREAT Asia HIV Observational Database (TAHOD-LITE).Antiviral therapy · 2018Article
- Trends in CD4 cell count response to first-line antiretroviral treatment in HIV-positive patients from Asia, 2003-2013: TREAT Asia HIV Observational Database Low Intensity Transfer.International journal of STD & AIDS · 2017Article
- Article
- Loss to Follow-up Trends in HIV-Positive Patients Receiving Antiretroviral Treatment in Asia From 2003 to 2013.Journal of acquired immune deficiency syndromes (1999) · 2017Article
- HIV and Aging: Demographic Change in the Asia-Pacific Region.Journal of acquired immune deficiency syndromes (1999) · 2017Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundAntiretroviral treatment (ART) for HIV-positive patients has expanded rapidly in Asia over the last 10 years. Our study aimed to describe the time trends and risk factors for overall survival in patients receiving first-line ART in Asia.
methodsWe included HIV-positive adult patients who initiated ART between 2003-2013 (n=16,546), from seven sites across six Asia-Pacific countries. Patient follow-up was to May 2014. We compared survival for each country and overall by time period of ART initiation using Kaplan-Meier curves. Factors associated with mortality were assessed using Cox regression, stratified by site. We also summarized first-line ART regimens, CD4
resultsThere were 880 deaths observed over 54,532 person-years of follow-up, a crude rate of 1.61 (95% CI 1.51, 1.72) per 100 person-years. Survival significantly improved in more recent years of ART initiation. The survival probability at 4 years follow-up for those initiating ART in 2003-2005 was 92.1%, 2006-2009 was 94.3% and 2010-2013 was 94.5% (P<0.001). Factors associated with higher mortality risk included initiating ART in earlier time periods, older age, male sex, injecting drug use as HIV exposure and lower pre-ART CD4
conclusionsOur results suggest that HIV-positive patients from Asia have improved survival in more recent years of ART initiation. This is likely a consequence of improvements in treatment, patient management and monitoring over time.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.