Evidence map›Paper›PMID 26961306›Full record

ArticleNeuroradiology2016

Enhanced gray-white matter differentiation on non-enhanced CT using a frequency selective non-linear blending.

Georg Bier, Malte Niklas Bongers, Hendrik Ditt, Benjamin Bender, Ulrike Ernemann, Marius Horger

Abstract read
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In one paragraph

Article in Neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Georg BierDepartment of Diagnostic and Interventional Radiology, Eberhard Karls-University Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany. georghomann@web.de.
Malte Niklas BongersDepartment of Diagnostic and Interventional Radiology, Eberhard Karls-University Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.
Hendrik DittImaging & Therapy Division, Siemens AG Healthcare Sector, Forchheim, Germany.
Benjamin BenderDepartment of Neuroradiology, Eberhard Karls-University Tuebingen, Tuebingen, Germany.
Ulrike ErnemannDepartment of Neuroradiology, Eberhard Karls-University Tuebingen, Tuebingen, Germany.
Marius HorgerDepartment of Diagnostic and Interventional Radiology, Eberhard Karls-University Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.
University of Tübingen · DESiemens Healthcare (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim if this study is to find out if contrast between gray (GM) and white matter (WM) on non-enhanced brain CT (NECT) can be enhanced by using a frequency selective non-linear blending.

methodsThirty consecutive patients (40 % female; mean age 67.73 ± 12.71 years), who underwent NECT of the brain, were retrospectively included in this study. Brain scan readings were performed by two radiologists independently, for NECT and subsequently the images were read using a new frequency selective non-linear blending algorithm (best contrast, BC). Optimal settings of BC for enhanced delineation of anatomical structures were set at an averaged center of 30 HU, averaged delta of 5 HU, and a slope of 5. For contrast-to-noise ratio calculation (CNR), gray and white matter attenuation values were measured for both NECT and BC in different anatomical structures.

resultsCNR increase in the gray matter was 5.91 ± 2.45 for the cortical gray matter and 4.41 ± 1.82 for the basal ganglia. The contrast ratio between cortical gray and white matter was 1.87 and 1.7 (basal ganglia/WM) for BC quantification vs. 1.43 (cortex/WM) and 1.33 (basal ganglia/WM) for standard NECT (both p < 0.0001). Improved CNR did not depend on the anatomical structures measured.

conclusionFrequency selective non-linear blending allows better discrimination between WM and GM and therefore may enhance diagnostic accuracy of NECT.

Indexed as

AgedAlgorithmsBrainFemaleGray MatterHumansMaleMultidetector Computed TomographyNonlinear DynamicsRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsSensitivity and SpecificitySignal-To-Noise RatioWhite MatterContrast-to-noise-ratioGray matterImage post-processingMultidetector computed tomographyWhite matter

Identifiers

PMID26961306
OpenAlexW2295986597

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.