ArticleInternational orthopaedics2016
The incidence and risk factors for post-operative ileus after spinal fusion surgery: a multivariate analysis.
Article in International orthopaedics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Postoperative bowel complications after non-shunt-related neurosurgical procedures: case series and review of the literature.Neurosurgical review · 2022Pooled it
- Effect of Chewing Gum on Bowel Function Recovery in Elderly Patients Following Posterior Lumbar Fusion Surgery: A Randomized Controlled Trial.Orthopaedic surgery · 2026Trial
- Pre-operative carbohydrate drink in pediatric spine fusion: randomized control trial.Spine deformity · 2024Trial
- Early postoperative hypophosphatemia is an independent predictor of ileus after transforaminal lumbar interbody fusion: a multicenter retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Evaluating the incidence of ileus in patients with pelvic ring and acetabular fractures in Major Trauma: a retrospective cohort audit at a Major Trauma Centre (July 2024-June 2025).European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Is the antepsoas oblique lumbosacral interbody fusion safe in patients with aortoiliac calcification?North American Spine Society journal · 2026Article
- Development and comparison of machine learning models for predicting postoperative ileus after posterior thoracolumbar fracture surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Risk factors for postoperative ileus following transforaminal lumbar interbody fusion: a retrospective study.Journal of orthopaedic surgery and research · 2025Article
- Underestimation of postoperative ileus as a benign complication in spine surgery: a case-control study in a major spine surgery centre in Saudi Arabia.Journal of spine surgery (Hong Kong) · 2025Article
- Incidence and Risk Factors of Postoperative Ileus in Oblique Lumbar Interbody Fusion Surgery: A Retrospective Study.Neurospine · 2025Article
- Utility of Abdominal Radiographs After Posterior Spinal Fusion for Neuromuscular Scoliosis.Journal of clinical medicine · 2025Article
- Anterior lumbar interbody fusion: patient selection and workup.Journal of spine surgery (Hong Kong) · 2024Review
- Validity of the I‑FEED classification in assessing postoperative gastrointestinal impairment in patients undergoing elective lumbar spinal surgery with general anesthesia: a prospective observational study.Perioperative medicine (London, England) · 2024Article
- Risk Factors for Postoperative Ileus Following Spine Surgery: A Systematic Review With Meta-Analysis.Global spine journal · 2024Article
- Risk Factors for Postoperative Ileus in Patients Undergoing Spine Surgery.Global spine journal · 2023Article
- Incidence and Risk Factors for Postoperative Ileus after Posterior Surgery in Adolescent Idiopathic Scoliosis.Orthopaedic surgery · 2023Article
- What Are Risk Factors for an Ileus After Posterior Spine Surgery?-A Case Control Study.Global spine journal · 2022Article
- The Role of Inflammatory Mediators in the Development of Gastrointestinal Motility Disorders.International journal of molecular sciences · 2022Review
- Risk Factors for Postoperative Ileus after Scoliosis Surgery.Spine surgery and related research · 2018Article
- Minimally invasive transaxial lumbosacral interbody fusion: a ten year single-centre experience.International orthopaedics · 2017Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePost-operative ileus is a recognized complication of surgery. Little is known about the incidence and risk factors for post-operative ileus following spinal fusion surgery. To report the incidence and to assess for independent risk factors of post-operative ileus after spinal fusion surgery.
methodsRetrospective single-centre cohort study. Patients with prolonged or recurrent post-operative ileus were identified by review of hospital stay documentation. Patients with post-operative ileus were matched 1:2 to a control cohort without post-operative ileus. Uni and multi variate analyses were performed on demographic, comorbidity, surgical indication, medication, and peri-operative details to identify risk factors for post-operative ileus.
resultsTwo thousand six hundred and twenty five patients underwent spinal fusion surgery between January 2012 and December 2012. Forty nine patients with post-operative ileus were identified (1.9 %). Post-operative length of hospital stay was significantly longer for patients with post-operative ileus (9.3 ± 5.2 days), than control patients (5.5 ± 3.2 days) (p < 0.001). Independent risk factors were Lactated Ringers solution (aOR: 2.12, p < 0.001), 0.9 % NaCl solution (aOR: 2.82, p < 0.001), and intra-operative hydromorphone (aOR: 2.31, p < 0.01) and a history of gastro-oesophageal reflux (aOR: 4.86, p = 0.03). Albumin administration (aOR: 0.09, p < 0.01) was protective against post-operative ileus.
conclusionsPost-operative ileus is multifactorial in origin, and this study identified intra-operative hydromorphone and post-operative crystalloid fluid administration ≥2 litres as independent risk factors for the development of ileus.
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