ReviewActa crystallographica. Section D, Structural biology2016
Radiation damage and derivatization in macromolecular crystallography: a structure factor's perspective.
Review in Acta crystallographica. Section D, Structural biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- An analysis of the structural changes of the oxygen evolving complex of Photosystem II in the SBiochimica et biophysica acta. Bioenergetics · 2025Review
- Guidelines for de novo phasing using multiple small-wedge data collection.Journal of synchrotron radiation · 2021Article
- Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography.Acta crystallographica. Section D, Structural biology · 2019Article
- Low-dose fixed-target serial synchrotron crystallography.Acta crystallographica. Section D, Structural biology · 2017Article
- OH cleavage from tyrosine: debunking a myth.Journal of synchrotron radiation · 2017Article
- Identification of the point of diminishing returns in high-multiplicity data collection for sulfur SAD phasing.Journal of synchrotron radiation · 2017Article
- Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography.Journal of synchrotron radiation · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During, or even after, data collection the presence and effects of radiation damage in macromolecular crystallography may not always be immediately obvious. Despite this, radiation damage is almost always present, with site-specific damage occurring on very short time (dose) scales well before global damage becomes apparent. A result of both site-specific radiation damage and derivatization is a change in the relative intensity of reflections. The size and approximate rate of onset of X-ray-induced transformations is compared with the changes expected from derivatization, and strategies for minimizing radiation damage are discussed.
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