Evidence map›Paper›PMID 26959493›Full record

ArticlePloS one2016

Generalized Scaling and the Master Variable for Brownian Magnetic Nanoparticle Dynamics.

Daniel B Reeves, Yipeng Shi, John B Weaver

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel B ReevesDepartment of Physics and Astronomy, Dartmouth College, Hanover, NH, 03755 United States of America.
Yipeng ShiDepartment of Physics and Astronomy, Dartmouth College, Hanover, NH, 03755 United States of America.
John B WeaverDepartment of Physics and Astronomy, Dartmouth College, Hanover, NH, 03755 United States of America.

Funding

Toxicology, Pathology and Biodistribution Core (TPB Core)U54CA151662 · NCI · DARTMOUTH COLLEGE · PI POGUE, BRIAN WILLIAM · 2010 to 2014
$11.6M
NCI NIH HHS 1U54CA151662-01NCI NIH HHS U54 CA151662
6 · The paper itself

Abstract

Understanding the dynamics of magnetic particles can help to advance several biomedical nanotechnologies. Previously, scaling relationships have been used in magnetic spectroscopy of nanoparticle Brownian motion (MSB) to measure biologically relevant properties (e.g., temperature, viscosity, bound state) surrounding nanoparticles in vivo. Those scaling relationships can be generalized with the introduction of a master variable found from non-dimensionalizing the dynamical Langevin equation. The variable encapsulates the dynamical variables of the surroundings and additionally includes the particles' size distribution and moment and the applied field's amplitude and frequency. From an applied perspective, the master variable allows tuning to an optimal MSB biosensing sensitivity range by manipulating both frequency and field amplitude. Calculation of magnetization harmonics in an oscillating applied field is also possible with an approximate closed-form solution in terms of the master variable and a single free parameter.

Indexed as

Models, TheoreticalBiosensing TechniquesComputer SimulationMagnetic FieldsMagnetite NanoparticlesReproducibility of ResultsTemperatureMagnetite Nanoparticles

Identifiers

PMID26959493
PMCPMC4784917

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.