Evidence map›Paper›PMID 26958918›Full record

ReviewAnnual review of virology2015

Modulation of the Translational Landscape During Herpesvirus Infection.

Britt A Glaunsinger

Abstract readReview
In one paragraph

Review in Annual review of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Britt A GlaunsingerDepartment of Plant and Microbial Biology, University of California, Berkeley, California 94720; email: glaunsinger@berkeley.edu.

Funding

Disruption of Cellular RNA Processing by Kaposi's Sarcoma-Associated HerpesvirusR01CA136367 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Britt A Glaunsinger · 2010 to 2026
$5.8M
Escape from gammaherpesvirus-induced mRNA destructionR01CA160556 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI GLAUNSINGER, BRITT A · 2011 to 2015
$1.5M
NCI NIH HHS CA136367NCI NIH HHS CA160556NCI NIH HHS R01 CA136367NCI NIH HHS R01 CA160556
6 · The paper itself

Abstract

Herpesviral mRNAs are produced and translated by cellular machinery, rendering them susceptible to the network of regulatory events that impact translation. In response, these viruses have evolved to infiltrate and hijack translational control pathways as well as to integrate specialized host translation strategies into their own repertoire. They are robust systems to dissect mechanisms of mammalian translational regulation and continue to offer insight into cis-acting mRNA features that impact assembly and activity of the translation apparatus. Here, I discuss recent advances revealing the extent to which the three herpesvirus subfamilies regulate both host and viral translation, thereby dramatically impacting the landscape of protein synthesis in infected cells.

Indexed as

Protein BiosynthesisAnimalsFlaviviridae InfectionsGene Expression Regulation, ViralHerpesviridaeHumansViral ProteinsViral ProteinseIF4Fherpesvirusprotein kinase Rtranslationunfolded protein responseuORF

Identifiers

PMID26958918
PMCPMC4921129

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.