Evidence map›Paper›PMID 26958609›Full record

ArticleData in brief2015

Supporting data for analysis of the Helicobacter pylori exoproteome.

Christina A Snider, Bradley J Voss, W Hayes McDonald, Timothy L Cover

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christina A SniderDepartment of Medicine, Nashville, TN, USA.
Bradley J VossDepartment of Pathology, Microbiology and Immunology, Nashville, TN, USA.
W Hayes McDonaldProteomics Laboratory, Mass Spectrometry Research Center, Nashville, TN, USA; Department of Biochemistry, Nashville, TN, USA.
Timothy L CoverDepartment of Medicine, Nashville, TN, USA; Department of Pathology, Microbiology and Immunology, Nashville, TN, USA; Vanderbilt University School of Medicine; Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN, USA.

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 2009 to 2026
$27.5M
Structure-function analysis of H. pylori VacAR01AI039657 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 1996 to 2026
$8.3M
Pathogenesis of Helicobacter pylori infectionI01BX000627 · VA · VETERANS HEALTH ADMINISTRATION · PI COVER, TIMOTHY L · 2011 to 2018
–
BLRD VA I01 BX000627NCI NIH HHS P01 CA116087NCI NIH HHS P30 CA068485NIAID NIH HHS R01 AI039657NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

The goal of this research was to analyze the composition of the Helicobacter pylori exoproteome at multiple phases of bacterial growth (Snider et al., 2015) [1]. H. pylori was grown in a serum-free medium and at serial time points, aliquots were centrifuged and fractionated to yield culture supernatant, a soluble cellular fraction, and a membrane fraction. Samples were analyzed by single dimensional LC-MS/MS analyses and multidimensional protein identification technology (MudPIT). Here we present data showing the numbers of assigned spectra and proportional abundance of individual proteins in each of the samples analyzed, along with a calculation of the level of enrichment of individual proteins in the supernatant compared to the soluble cellular fraction.

Indexed as

Bacterial protein secretionExoproteomeGastric cancerMass spectrometryPeptic ulcer diseaseProteomicsSecretome

Identifiers

PMID26958609
PMCPMC4773364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.