ArticleCaspian journal of internal medicine2016
Salivary oxidant/ antioxidant status and hematological parameters in patients with recurrent aphthous stomatitis.
Article in Caspian journal of internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Systemic and local effect of oxidative stress on recurrent aphthous stomatitis: systematic review.Journal of molecular medicine (Berlin, Germany) · 2024Pooled it
- Hematological parameters in patients with recurrent Aphthous Stomatitis: a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Systematic review and meta-analysis of oxidative stress and antioxidant markers in recurrent aphthous stomatitis.BMC oral health · 2023Pooled it
- The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis.BioMed research international · 2018Trial
- Oxidative Stress Biomarkers in Oral Mucosal Wound Healing and Photobiomodulation: Biochemical Pathways, Experimental Models, and Translational Perspectives.International journal of molecular sciences · 2026Review
- Periplaneta americana extract improves recurrent oral ulcers through regulation of TLR4/NF-κB and Nrf2/HO-1 pathways.Scientific reports · 2025Article
- Exploring the Potential of Bee-Derived Antioxidants for Maintaining Oral Hygiene and Dental Health: A Comprehensive Review.Antioxidants (Basel, Switzerland) · 2023Review
- Oral Sources of Salivary Metabolites.Metabolites · 2023Review
- Evaluation of saliva glutathione, glutathione peroxidase, and malondialdehyde levels in head-neck radiotherapy patientsTurkish journal of medical sciences · 2021Article
- Penicillin in oral aphthosis, new insight for an old drug: A randomized, double-blind, controlled clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020Article
- Salivary metabolomics profile of patients with recurrent aphthous ulcer as revealed by liquid chromatography-tandem mass spectrometry.The Journal of international medical research · 2018Article
- Hematinic deficiencies in patients with recurrent aphthous stomatitis: variations by gender and age.Medicina oral, patologia oral y cirugia bucal · 2018Article
- Salivary Oxidant/Antioxidant Status in Chronic Temporomandibular Disorders Is Dependent on Source and Intensity of Pain - A Pilot Study.Frontiers in physiology · 2018Article
- Evaluation and Comparison of Total Antioxidant Capacity of Saliva Between Patients with Recurrent Aphthous Stomatitis and Healthy Subjects.The open dentistry journal · 2018Article
- Assessment of serum malondialdehyde, uric acid, and vitamins C and E levels in patients with recurrent aphthous stomatitis.Journal of dental sciences · 2016Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecurrent aphthous stomatitis (RAS) is the most common inflammatory ulcerative condition of oral cavity. The aim of this study was to compare the levels of the salivary Malondialdehyde (MDA) and total antioxidant capacity (TAC) and blood parameter in RAS versus healthy controls.
methodsThis case-control study consisted of 28 patients with RAS and 28 age and sex -matched control without RAS. Cell blood count was assessed by sysmex system, serum iron and total iron binding capacity was measured by standard laboratory kit and for ferritin ELISA kit was utilized. Salivary TAC and MDA level determined using FRAP and TBARS method respectively. Statistical analysis was performed using SPSS Version 21, chi-square test was used to compare proportions, and student's t-test and Mann Whitney U-test were used for the comparison of quantitative variables.
resultsSalivary MDA level was significantly higher (p<0.001) and TAC level was significantly lower (p<0.042) in RAS as compared with the control group. Also, serum ferritin level was significantly higher in RAS patients (p<0.008).
conclusionThese findings indicate the alteration of oxidant/antioxidant status was observed in recurrent aphthous stomatitis, may be also associated with changing several hematinic parameters in this study. The finding maybe helpful to clarify the etiologies of RAS and possibely to improve the management or preventive options.
Indexed as
Identifiers
26958327PMC4761117W2201069273What OpenQuestion holds
Registered trials
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