Evidence map›Paper›PMID 26958279›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2015

Using a Clinical Knowledge Base to Assess Comorbidity Interrelatedness Among Patients with Multiple Chronic Conditions.

Donna M Zulman, Susana B Martins, Yan Liu, Samson W Tu, Brian B Hoffman, Steven M Asch, Mary K Goldstein

Open access · greenAbstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Article
  5. High-Risk Drug-Drug Interactions Between Clinical Practice Guidelines for Management of Chronic Conditions.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Donna M ZulmanCenter for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, CA; Division of General Medical Disciplines, Stanford University, Stanford, CA.
Susana B MartinsGeriatrics Research Education and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA.
Yan LiuDepartment of Biomedical, Industrial, and Human Factors Engineering, Wright State University, Dayton, OH.
Samson W TuBiomedical Informatics Research (BMIR), Stanford University School of Medicine, Stanford, CA.
Brian B HoffmanVA Boston Health Care System, West Roxbury Division, Boston, MA; Harvard Medical School, Boston, MA.
Steven M AschCenter for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, CA; Division of General Medical Disciplines, Stanford University, Stanford, CA.
Mary K GoldsteinGeriatrics Research Education and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA; Center for Primary Care and Outcomes Research (PCOR), Stanford University School of Medicine, Stanford, CA.
Stanford University · USVA Palo Alto Health Care System · USWright State University · US

Funding

Intramural VA VA999999
6 · The paper itself

Abstract

Decision support tools increasingly integrate clinical knowledge such as medication indications and contraindications with electronic health record (EHR) data to support clinical care and patient safety. The availability of this encoded information and patient data provides an opportunity to develop measures of clinical decision complexity that may be of value for quality improvement and research efforts. We investigated the feasibility of using encoded clinical knowledge and EHR data to develop a measure of comorbidity interrelatedness (the degree to which patients' co-occurring conditions interact to generate clinical complexity). Using a common clinical scenario-decisions about blood pressure medications in patients with hypertension-we quantified comorbidity interrelatedness by calculating the number of indications and contraindications to blood pressure medications that are generated by patients' comorbidities (e.g., diabetes, gout, depression). We examined properties of comorbidity interrelatedness using data from a decision support system for hypertension in the Veterans Affairs Health Care System.

Indexed as

Electronic Health RecordsKnowledge BasesMultiple Chronic ConditionsComorbidityDecision Support TechniquesDiabetes MellitusHumans

Identifiers

PMID26958279
PMCPMC4765555
OpenAlexW2412152865

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.