Evidence map›Paper›PMID 26958210›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2015

Supporting Multi-sourced Medication Information in i2b2.

Jeffrey G Klann, Pascal B Pfiffner, Marc D Natter, Emily Conner, Paul Blazejewski, Shawn N Murphy, Kenneth D Mandl

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey G KlannPartners Healthcare, Boston, MA;; Harvard Medical School, Boston, MA;; Massachusetts General Hospital, Boston, MA;
Pascal B PfiffnerHarvard Medical School, Boston, MA;; Boston Children's Hospital, Boston MA;
Marc D NatterHarvard Medical School, Boston, MA;; Boston Children's Hospital, Boston MA;
Emily ConnerAnotera, LLC.
Paul BlazejewskiBoston Children's Hospital, Boston MA;
Shawn N MurphyPartners Healthcare, Boston, MA;; Harvard Medical School, Boston, MA;; Massachusetts General Hospital, Boston, MA;
Kenneth D MandlHarvard Medical School, Boston, MA;; Boston Children's Hospital, Boston MA;

Funding

Instrumenting i2b2 for Improved Medication Research: Adding the Patient VoiceR01GM104303 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI MANDL, KENNETH D. · 2013 to 2016
$1.6M
NIGMS NIH HHS R01 GM104303
6 · The paper itself

Abstract

Postmarketing drug surveillance is critical to assessing adverse events associated with medications, because prelaunch clinical trials frequently miss negative drug effects. The Informatics for Integrating Biology and the Bedside platform (i2b2) has been used effectively for this. However, previous work suffers from incomplete medical data present in electronic health record (EHR) systems. Here, we develop a system to integrate non-traditional data sources with EHR data: pharmacy dispensing information and patient-reported data. We implement and validate a toolset to gather medication data from a Pharmacy Benefit Manager network, import it into an i2b2 EHR repository using a standard data format, merge it with the EHR data, and present it to for annotation with results returned to i2b2. This toolkit is enabling studies on medication list data quality, adherence, and adverse event detection.

Indexed as

Electronic Health RecordsInformation Storage and RetrievalSoftwareBiomedical ResearchHealth Information InteroperabilityHumansPharmaciesProduct Surveillance, PostmarketingProgramming Languages

Identifiers

PMID26958210
PMCPMC4765563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.