Evidence map›Paper›PMID 26958183›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2015

Semi-supervised Learning for Phenotyping Tasks.

Dmitriy Dligach, Timothy Miller, Guergana K Savova

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Pre-training phenotyping classifiers.Journal of biomedical informatics · 2021
    Article
  2. DDL: Deep Dictionary Learning for Predictive Phenotyping.IJCAI : proceedings of the conference · 2019
    Article
  3. Clinical Document Classification Using Labeled and Unlabeled Data Across Hospitals.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dmitriy DligachBoston Children's Hospital and Harvard Medical School, Boston, MA.
Timothy MillerBoston Children's Hospital and Harvard Medical School, Boston, MA.
Guergana K SavovaBoston Children's Hospital and Harvard Medical School, Boston, MA.

Funding

Informatics for Integrating Biology/ the Bedside (RMI)U54LM008748 · NLM · BRIGHAM AND WOMEN'S HOSPITAL · PI KOHANE, ISAAC S. · 2004 to 2013
$39.0M
Cancer Deep Phenotype Extraction from Electronic Medical RecordsU24CA184407 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SAVOVA, GUERGANA K. · 2014 to 2018
$4.4M
Annotation, development and evaluation for clinical information extraction (transfer)R01GM090187 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHAPMAN, WENDY W., ELHADAD, NOEMIE · 2010 to 2013
$2.6M
Informatics Tools for Pharmacogenomic Discovery using Practice-based DataR01GM103859 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DENNY, JOSHUA C., PATHAK, JYOTISHMAN · 2014 to 2017
$2.4M
NCI NIH HHS U24 CA184407NIGMS NIH HHS R01 GM090187NIGMS NIH HHS R01 GM103859NLM NIH HHS U54 LM008748
6 · The paper itself

Abstract

Supervised learning is the dominant approach to automatic electronic health records-based phenotyping, but it is expensive due to the cost of manual chart review. Semi-supervised learning takes advantage of both scarce labeled and plentiful unlabeled data. In this work, we study a family of semi-supervised learning algorithms based on Expectation Maximization (EM) in the context of several phenotyping tasks. We first experiment with the basic EM algorithm. When the modeling assumptions are violated, basic EM leads to inaccurate parameter estimation. Augmented EM attenuates this shortcoming by introducing a weighting factor that downweights the unlabeled data. Cross-validation does not always lead to the best setting of the weighting factor and other heuristic methods may be preferred. We show that accurate phenotyping models can be trained with only a few hundred labeled (and a large number of unlabeled) examples, potentially providing substantial savings in the amount of the required manual chart review.

Indexed as

AlgorithmsElectronic Health RecordsDatasets as TopicDiseaseHumansInformation Storage and RetrievalSupervised Machine Learning

Identifiers

PMID26958183
PMCPMC4765699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.