ArticleAfrican health sciences2015
Proportion of patients in the Uganda rheumatic heart disease registry with advanced disease requiring urgent surgical interventions.
Article in African health sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03346525 (The GOAL), which is not on this map. Cited by 16 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The GOAL (GwokO Adunu pa Lutino) Trial: Determining the Impact of Penicillin on Latent Rheumatic Heart Disease: A Randomized Controlled Trial in Uganda
Who cites it
16 citing papers in PubMed.
- Cost-Effectiveness Analysis of Surgical Strategies Versus Medical Management for Rheumatic Heart Disease in Rwanda.Journal of the American Heart Association · 2025Article
- The roles of immuno-modulator treatment and echocardiographic screening in rheumatic fever and rheumatic heart disease control: research from Aotearoa, New Zealand.Journal of the Royal Society of New Zealand · 2025Review
- Tertiary prevention and treatment of rheumatic heart disease: a National Heart, Lung, and Blood Institute working group summary.BMJ global health · 2023Review
- Health related quality of life of patients following mechanical valve replacement surgery for rheumatic mitral stenosis in Tanzania.Journal of cardiothoracic surgery · 2023Article
- Clinical Profile and Outcomes of Rheumatic Heart Disease Patients Undergoing Surgical Valve Procedures in Uganda.Global heart · 2023Article
- Modelling study of the ability to diagnose acute rheumatic fever at different levels of the Ugandan healthcare system.BMJ open · 2022Article
- Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward.Frontiers in cardiovascular medicine · 2022Review
- The Global Impact of Rheumatic Heart Disease.Current cardiology reports · 2021Review
- Examining the Ugandan health system's readiness to deliver rheumatic heart disease-related services.PLoS neglected tropical diseases · 2021Article
- Rheumatic Heart Disease is Missing from the Global Health Agenda.Annals of global health · 2021Review
- Decreased Prevalence of Rheumatic Heart Disease Confirmed Among HIV-positive Youth.The Pediatric infectious disease journal · 2019Article
- Outcomes for patients with rheumatic heart disease after cardiac surgery followed at rural district hospitals in Rwanda.Heart (British Cardiac Society) · 2018Article
- Prevalence and characteristics of primary left-sided valve disease in a cohort of 15,000 patients undergoing echocardiography studies in a tertiary hospital in Uganda.BMC cardiovascular disorders · 2018Article
- Rheumatic heart disease: infectious disease origin, chronic care approach.BMC health services research · 2017Review
- From sexual orientation to cochlear transplants in a tropical environment.African health sciences · 2015Article
- From Accra to Kampala: Ghana's cardiothoracic legacy and the unfinished agenda for rheumatic heart disease in East Africa.Therapeutic advances in cardiovascular diseaseArticle
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Authors and funding
5 authors.
Funding
Abstract
introductionSince the establishment of the Uganda Rheumatic Heart Registry, over 900 patients have been enrolled. We sought to stratify the patients in the registry according to disease severity and optimal management strategy.
methodsWe reviewed data of 618 patients who had enrolled in the Registry between March 2010 and February 2013. The 67 patients who had died were excluded leaving 551 patients who were recruited. The optimum management strategy was determined according to the 2012 European Society of Cardiology guidelines on the management of valvular heart disease.
resultsOut of the 551 patient's records evaluated, 398 (72.3%) required invasive intervention, with 332(60.3%) patients requiring surgery and 66 (12.0%) requiring percutaneous mitral commissurotomy (PMC). This leaves only 27.7% of patients who required only medical management. Currently, majority of the patients (498, 90.4%) in the registry are on medical treatment. Of the 60.3% requiring surgical intervention, only 8.0% (44 patients) underwent valvular surgery and 5(1.0%) patients of the 66 (12.0%) underwent PMC successfully.
conclusionThere is a high proportion of patients with severe disease that require surgical treatment yet they cannot access this therapy due to absence of local expertise.
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