Evidence map›Paper›PMID 26958008›Full record

ArticleAfrican health sciences2015

Prevalence of intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp-SP) use during pregnancy and other associated factors in Sekondi-Takoradi, Ghana.

Verner N Orish, Onyekachi S Onyeabor, Johnson N Boampong, Richmond Afoakwah, Ekene Nwaefuna, Samuel Acquah, Adekunle O Sanyaolu, Nnaemeka C Iriemenam

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Verner N OrishDepartment of Internal Medicine, Effia-Nkwanta Regional Hospital Sekondi-Takoradi, Sekondi P. O. Box 229, Western Region, Ghana.
Onyekachi S OnyeaborThe Satcher Health Leadership Institute, Department of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, Georgia, USA.
Johnson N BoampongDepartment of Human Biology, University of Cape Coast, Cape Coast, Central Region, Ghana.
Richmond AfoakwahDepartment of Human Biology, University of Cape Coast, Cape Coast, Central Region, Ghana.
Ekene NwaefunaBiotechnology and Nuclear Agriculture Research Institute, Atomic Energy Commission, Accra, Ghana.
Samuel AcquahDepartment of Medical Biochemistry, School of Medical Sciences, University of Cape Coast, Ghana.
Adekunle O SanyaoluDepartment of Medical Microbiology and Parasitology, College of Medicine of the University of Lagos, Idi-araba, PMB 12003 Lagos, Nigeria; Saint James School of Medicine, Anguilla, BWI.
Nnaemeka C IriemenamDepartment of Medical Microbiology and Parasitology, College of Medicine of the University of Lagos, Idi-araba, PMB 12003 Lagos, Nigeria.
University of Cape Coast · GHUniversity of Lagos · NGGhana Atomic Energy Commission · GHMorehouse School of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) has been adopted as policy by most countries in sub-Saharan Africa. This cross-sectional study assessed the prevalence of IPTp-SP usage for prevention of malaria among pregnant women as well as evaluated factors associated with IPTp-SP use during pregnancy in Sekondi-Takoradi region of Ghana.

methodsPregnant women attending their antenatal-care with either clinical/ultrasound evidence of pregnancy were recruited. Venous blood was screened for malaria using RAPID response antibody kit and Giemsa staining. Haemoglobin estimations were done by cyanmethemoglobin method while Human Immunodeficiency Virus (HIV) screening was performed by the national diagnostic algorithm of two rapid antibody test and western blot confirmation.

resultsOf the 754 consented pregnant women interviewed in this study, 57.8% had received IPTp-SP while 42.2% had not at their first contact with the study personnel. Furthermore, 18.6% (81/436) of those that received IPTp-SP were malaria positive while 81.4% (355/436) were malaria negative. The results also indicated that 47.7% (51/107) of the pregnant women in their third trimester who were meant to have received at least two-doses of SP had received ≥2 doses while 35.5% (38/107) had received 1 dose. In multivariable logistic regression analysis, pregnant women in their third trimester who received ≥2 doses of SP showed decreased likelihoods of malaria (adjusted OR, 0.042; 95% CI, 0.003-0.51; P = 0.013).

conclusionIPTp-SP usage among pregnant women in Sekondi-Takoradi reduces malaria and its use for malaria prevention should be strengthened with proper dosage completion and coverage.

Indexed as

AdolescentAdultAntimalarialsCross-Sectional StudiesDose-Response Relationship, DrugDrug CombinationsFemaleGhanaHumansMalariaPregnancyPregnancy Complications, ParasiticPrenatal CarePyrimethamineRegression AnalysisSocioeconomic FactorsAntimalarialsDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxineanaemiaGhanaIPTp-SPMalaria in pregnancy

Identifiers

PMID26958008
PMCPMC4765396
OpenAlexW2289935716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.