Evidence map›Paper›PMID 26957987›Full record

ArticleAfrican health sciences2015

Upper gastrointestinal diseases in patients for endoscopy in South-Western Uganda.

Siraji Obayo, Conrad Muzoora, Ponsiano Ocama, Matthew M Cooney, Tony Wilson, Christopher S Probert

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Siraji ObayoMbarara University Teaching Hospital, Mbarara, Uganda and the Uganda Cancer Institute, Kampala, Uganda.
Conrad MuzooraMbarara University Teaching Hospital, Mbarara Uganda.
Ponsiano OcamaInfectious Diseases Institute, Research; Makerere University.
Matthew M CooneyCase Western Reserve University, Case Comprehensive Cancer Center, Cleveland, Ohio, USA.
Tony WilsonMbarara University Teaching Hospital, Mbarara Uganda.
Christopher S ProbertInstitute of Translational Medicine, University of Liverpool United Kingdom.
Mbarara National Referral Hospital · UGCase Comprehensive Cancer CenterUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a paucity of published data regarding upper gastrointestinal diseases in Ugandans with upper gastrointestinal symptoms referred for endoscopy.

objectivesTo study the presenting complaints, pathology and Helicobacter pylori prevalence among patients with upper gastrointestinal symptoms in South-Western Uganda.

methodsPatients presenting with upper gastrointestinal symptoms underwent upper endoscopy and a urease test for Helicobacter Pylori, all suspicious lesions were biopsied for histopathology review as appropriate.

resultsThe most common presenting complaints were epigastric pain (51.6%), dysphagia (13.6%) and odynophagia (7.1%). The most common endoscopy finding was gastritis (40.2%), followed by normal examination (15.2%), oesophageal cancer (13.6%), gastric ulcer (7.6%) and gastric cancer (7.1%). Patients older than 40 years (n=110) had significant findings including gastritis (50.9%), oesophageal cancer (22.7%) and gastric cancer (11.8%). However in younger patients, with the age range of 18-40 years (n=74), most examinations were normal (92.9%). Of the 176 patients able to undergo Helicobacter pylori testing 75.6% were positive. Helicobacter pylori infection was associated with statistically significant increase in gastritis, oesophageal cancer, gastric ulcer, gastric cancer, and duodenal ulcers (p-values< 0.05).

conclusionGastritis, ulcerative disease, and upper gastrointestinal malignancies are common in South-Western Ugandans and are associated with a high prevalence of Helicobacter pylori.

Indexed as

Endoscopy, GastrointestinalAdolescentAdultAgedAged, 80 and overAge DistributionBiopsyChildCross-Sectional StudiesDuodenal UlcerFemaleGastritisGastrointestinal DiseasesHelicobacter InfectionsHelicobacter pyloriHumansEndoscopyHelicobacter pyloriPathologyUgandaUpper gastrointestinal symptomsUrease test

Identifiers

PMID26957987
PMCPMC4765465
OpenAlexW1753968347

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.