Evidence map›Paper›PMID 26957974›Full record

ArticleAfrican health sciences2015

Prevalence and risk factors of latent Tuberculosis among adolescents in rural Eastern Uganda.

Daniel Mumpe-Mwanja, Suzanne Verver, Adoke Yeka, Alfred Etwom, James Waako, Willy Ssengooba, Joseph Kb Matovu, Rhoda K Wanyenze, Phillipa Musoke, Harriet Mayanja-Kizza

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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  7. Tuberculosis Infection in Children and Adolescents.Pathogens (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Daniel Mumpe-MwanjaMakerere University School of Public Health, CDC fellowship program; Makerere University, Iganga Mayuge Health Demographic Surveillance Site; Makerere University College of Health Sciences, Infectious Diseases Institute; Ministry of Health, National Tuberculosis and Leprosy Program.
Suzanne VerverKNCV Tuberculosis Foundation; CINIMA, Academic Medical Centre.
Adoke YekaMakerere University School of Public Health, Department of Disease control and Environmental Health.
Alfred EtwomMinistry of Health, National Tuberculosis and Leprosy Program.
James WaakoMakerere University, Iganga Mayuge Health Demographic Surveillance Site; Makerere University College of Health Sciences, Infectious Diseases Institute.
Willy SsengoobaMakerere University School of Medicine, Department of Microbiology; Makerere University College of Health Sciences, Infectious Diseases Institute.
Joseph Kb MatovuMakerere University School of Public Health, CDC fellowship program.
Rhoda K WanyenzeMakerere University School of Public Health, CDC fellowship program; Makerere University School of Public Health, Department of Disease control and Environmental Health.
Phillipa MusokeMakerere University College of Health Sciences, Infectious Diseases Institute; Makerere University School of Medicine, Department of Pediatrics and Child Health.
Harriet Mayanja-KizzaMakerere University School of Medicine, Department of Medicine; Makerere University College of Health Sciences, Infectious Diseases Institute.
Makerere University · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLatent Tuberculosis treatment is a key tuberculosis control intervention. Adolescents are a high risk group that is not routinely treated in low income countries. Knowledge of latent Tuberculosis (TB) burden among adolescents may influence policy.

objectivesWe determined the prevalence and risk factors of latent TB infection among adolescents in rural Uganda.

methodsWe analyzed baseline data from a study that assessed the prevalence and incidence of Tuberculosis disease among adolescents. We extracted socio-demographics, medical assessment information, and tuberculin skin test results and estimated prevalence ratios (PR) of latent TB infection risk factors by binomial regression.

resultsThe prevalence of latent TB was 16.1%, 95% CI (15.1 - 17.2). Significant risk factors were: a BCG scar, APR 1.29 (95% CI 1.12 - 1.48); male gender, APR 1.37 (95% CI 1.21 - 1.56); age 17 -18 years, APR 1.46 (95% CI 1.24 - 1.71) and 15-16 years, APR 1.25 (95% CI 1.07 - 1.46) compared to 12-14 years; being out of school, APR 1.31 (95% CI 1.05 - 1.62); and a known history of household TB contact in last 2 years, APR 1.91 (95% CI 1.55 - 2.35).

conclusionTargeted routine latent TB treatment among adolescents out of school may be crucial for TB disease control in low income countries.

Indexed as

AdolescentChildEpidemiologic StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansIncidenceLatent TuberculosisMaleMultivariate AnalysisPovertyPrevalenceRisk FactorsRural PopulationSocioeconomic FactorsTuberculin TestAdolescentsLatent tuberculosis infectionRisk factorsTuberculin skin testingTuberculosis

Identifiers

PMID26957974
PMCPMC4765437
OpenAlexW1842164495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.