ArticleAfrican health sciences2015
Variations in antimalarial components of Artemisia annua Linn from three regions of Uganda.
Article in African health sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 19 citations in OpenAlex.
- Exploration of the Antioxidant and Anti-inflammatory Potential ofPharmaceuticals (Basel, Switzerland) · 2023Article
- Diversity of bacterial community in the rhizosphere and bulk soil of Artemisia annua grown in highlands of Uganda.PloS one · 2023Article
- Artemisia Species with High Biological Values as a Potential Source of Medicinal and Cosmetic Raw Materials.Molecules (Basel, Switzerland) · 2022Review
- Danger of Herbal Tea: A Case of Acute Cholestatic Hepatitis Due toFrontiers in medicine · 2019Article
- A Systematic Review of Anti-malarial Properties, Immunosuppressive Properties, Anti-inflammatory Properties, and Anti-cancer Properties of Artemisia Annua.Electronic physician · 2016Review
- Hepatitis, HIV and Ebola: light at the end of the tunnel.African health sciences · 2015Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionArtemisia annua plant from the family Asteracea is a powerful antimalarial plant introduced to Uganda around 2003. In addition to the artemisinin component, the plant also contains flavonoids which work in synergy to artemisinin against malaria parasites. The plant also contains aromatic oils which repel mosquitoes. In this paper we report the variations in antimalarial components of A. annua samples from the regions cultivating it in Uganda.
methodsArtemisia annua samples were obtained from three regions that cultivated the plant at the time of this study. The samples were brought to laboratory, authenticated and processed. The levels of artemisinin, total flavonoids and aromatic components were quantified using high performance thin layer chromatography, ultra violet spectrophotometry and gas chromatography respectively.
resultsArtemisinin and total flavonoids levels were higher in samples obtained from high land areas (western and south western region) compared to that obtained from lowland regions (central) i.e 0.8% Vs 0.4% and 2.6% Vs 1.5% respectively. The aromatic oils (mosquito repellent components) were similar with camphor component being highest and levels ranging from 75.4% to 79.0%.
conclusionOur findings show that the active components in Artemisia annua cultivated and used in the Uganda vary with geographical regions and this calls for standardisation by source.
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