ArticleAfrican health sciences2015
Seropositivity and determinants of immunoglobulin-G (IgG) antibodies against Herpes simplex virus (HSV) types -1 and -2 in pregnant women in Port Harcourt, Nigeria.
Article in African health sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Seroprevalence of herpes simplex virus types 1 and 2 in Nigeria: a systematic review and meta-analyses.Pathogens and global health · 2019Pooled it
- The Effect of HSV-1 Seropositivity on the Course of Pregnancy, Childbirth and the Condition of Newborns.Microorganisms · 2022Article
- Research Progress on the Antiviral Activity of Glycyrrhizin and its Derivatives in Liquorice.Frontiers in pharmacology · 2021Review
- Review
- Hepatitis, HIV and Ebola: light at the end of the tunnel.African health sciences · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study is the first documented prevalence of IgG antibody against HSV-1&-2 in Port Harcourt, Nigeria and thus provides baseline data for future in-depth studies on HSV infection in South-South, Nigeria.
objectiveThis study determined the seropositivity and determinants of serum IgG antibody against HSV-1 & HIV-2 among pregnant women attending BMSH, Port Harcourt, Rivers State, Nigeria.
methodsSerum samples from 180 pregnant women attending antenatal clinic at Braithwaite Memorial Specialist Hospital (BMSH) in Port Harcourt, Nigeria. Serum samples were analysed with commercial HSV type-1&-2 specific IgG Enzyme Linked Immunosorbent Assay (ELISA) kits. Chi-square analysis was used to determine the association of infection with socio-demographic variables.
resultsOf the 180 pregnant women, 179 (99.4%) were seropositive and 1(0.6%) was seronegative for HSV 1&2 IgG antibody. No statistical association existed between the prevalence of HSV-1&-2 IgG antibodies and the socio-demographic variables studied (p>0.05) except for marital status which was significantly associated (p<0.05).
conclusionOur data shows that HSV-1 & 2 seropositivity among pregnant women in Port Harcourt is high; thus serological screening for HSV-1&-2 might be advisable for antenatal attendees.
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